MET activates PTK2 signaling

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PTK2HGF:p-4Y-MET dimer:PTK2HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimerATPADPHGF:p-4Y-MET dimer:p-Y397-PTK2Q9WUD9HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRCHGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRCHGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P17945 Hepatocyte growth factor
  • Hgf
view
P49134 Integrin beta-1
  • Itgb1
view
P97523 Hepatocyte growth factor receptor
  • Met
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025