primary ovarian insufficiency

Summary
Synonym
  • hypergonadotropic hypogonadism
  • premature ovarian failure
  • premature ovarian insufficiency
Definition
An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.
Super Class
ovarian disease
Disease Ontology
DOID:5426
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying all 6 entries
Gene ID Gene Symbol Description Source
4438 MSH4 mutS homolog 4
9210 BMP15 bone morphogenetic protein 15
27241 BBS9 Bardet-Biedl syndrome 9
57510 XPO5 exportin 5
147872 KASH5 KASH domain containing 5
254528 MEIOB meiosis specific with OB-fold

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025