GlyCosmos Portal

Submissions

Bone morphogenetic protein 15

Summary

UniProt ID

O95972

Gene Symbol

BMP15
GDF9B

Gene ID

[9210]

Organism

Homo sapiens (human)

External Links

GlyGen: O95972
PubChem: O95972
Re-Glyco: O95972

Annotation

Keyword: Cytokine Disease variant Disulfide bond Glycoprotein Growth factor Phosphoprotein Premature ovarian failure Proteomics identification Pyrrolidone carboxylic acid Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
cell surface receptor protein serine/threonine kinase signaling pathway	IBA	GO_REF
female gamete generation	TAS	PMID
female gamete generation	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway

reproductive process [inference]

multicellular organismal reproductive process [inference]

gamete generation [inference]

female gamete generation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
endoplasmic reticulum lumen	TAS	Reactome

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

Displaying **all 2** entries
GO Term	Evidence Code	Reference
cytokine activity	IBA	GO_REF
growth factor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVLLSILRILFLCELVLFMEHRAQMAEGGQSSIALLAEAPTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQLTRFNLSCHVEPWVQKNPTNHFPSSEGDSSKPSLMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWHGTSSLDIAFLLLYFNDTHKSIRKAKFLPRGMEEFMERESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	Source
87	N-linked (GlcNAc...) asparagine		UniProt GlyGen
147	N-linked (GlcNAc...) asparagine		UniProt GlyGen
237	N-linked (GlcNAc...) asparagine		UniProt GlyGen
277	O-linked (HexNAc...) threonine; in P17	18227435	UniProt GlyGen
373	N-linked (GlcNAc...) asparagine		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080494	ovarian dysgenesis 2	Alliance of Genome Resources
DOID:5426	primary ovarian insufficiency	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements