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cholesterol 25-hydroxylase like 2

Summary

Gene Symbol

ch25hl2

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

100136851

KEGG Gene ID

PubChem

100136851

Alliance of Genome Resources

ZFIN:ZDB-GENE-080204-82

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Iron
Metal-binding
Monooxygenase
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A223M0K5
A8WGT1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cholesterol metabolic process
lipid biosynthetic process	IEA
sterol biosynthetic process
cholesterol biosynthetic process via desmosterol	IBA
zymosterol biosynthetic process	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process

steroid biosynthetic process [inference]

sterol biosynthetic process

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

sterol biosynthetic process

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

zymosterol metabolic process [inference]

zymosterol biosynthetic process

lipid biosynthetic process

steroid biosynthetic process [inference]

sterol biosynthetic process

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol metabolic process [inference]

zymosterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process [inference]

cholesterol biosynthetic process via desmosterol

zymosterol biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
C-4 methylsterol oxidase activity	IBA
iron ion binding	IEA
steroid hydroxylase activity	IBA
oxidoreductase activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

monooxygenase activity [inference]

steroid hydroxylase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [inference]

C-4 methylsterol oxidase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [inference]

C-4 methylsterol oxidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	185268	WB:WBGene00018036

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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