GlyCosmos Portal

Submissions

sphingomyelin phosphodiesterase, acid-like 3B

Summary

Gene Symbol

Smpdl3b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

100340

KEGG Gene ID

PubChem

100340

Alliance of Genome Resources

MGI:1916022

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
GPI-anchor
Glycosidase
Inflammatory response
Innate immunity
Lipid degradation
Metal-binding
Reference proteome
Secreted
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TLX9
P58242

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
sphingomyelin catabolic process	IEA
inflammatory response
lipid catabolic process	IMP
negative regulation of toll-like receptor signaling pathway	IMP
innate immune response

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

sphingomyelin catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

sphingomyelin catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

sphingomyelin catabolic process

catabolic process [inference]

lipid catabolic process

phospholipid catabolic process [inference]

sphingomyelin catabolic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

sphingomyelin catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

phospholipid catabolic process [inference]

sphingomyelin catabolic process

sphingolipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin catabolic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

lipid catabolic process

phospholipid catabolic process [inference]

sphingomyelin catabolic process

sphingolipid catabolic process [inference]

sphingomyelin catabolic process

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space
plasma membrane	IDA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

side of membrane

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
sphingomyelin phosphodiesterase activity	IEA
protein binding	IPI
phosphoric diester hydrolase activity	ISO
phosphoric diester hydrolase activity	IDA
phosphoric diester hydrolase activity	IMP