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Guidelines

MIRAGE

phosphogluconate dehydrogenase

Summary

Gene Symbol

Pgd

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

100360180

KEGG Gene ID

PubChem

100360180

Alliance of Genome Resources

RGD:1583832

Annotation

Keyword

Acetylation
Cytoplasm
Gluconate utilization
NADP
Oxidoreductase
Pentose shunt
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6IUA3
P85968

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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2

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GO Term	Evidence Code	PMID
pentose-phosphate shunt	ISS
pentose-phosphate shunt	IDA
pentose-phosphate shunt	IEA
NADP+ metabolic process	IDA
NADPH regeneration	ISO

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

NADPH regeneration

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose biosynthetic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

D-gluconate metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose biosynthetic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

D-gluconate metabolic process

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration

carbohydrate derivative metabolic process [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA
cytosol	ISO
cytosol	IBA
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
phosphogluconate dehydrogenase (decarboxylating) activity	ISS
phosphogluconate dehydrogenase (decarboxylating) activity	ISO
phosphogluconate dehydrogenase (decarboxylating) activity	IDA
phosphogluconate dehydrogenase (decarboxylating) activity	IBA
phosphogluconate dehydrogenase (decarboxylating) activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

phosphogluconate dehydrogenase (decarboxylating) activity

binding [inference]

carbohydrate binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding

organic acid binding [inference]

carboxylic acid binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	110208	MGI:97553
Caenorhabditis elegans	177971	WB:WBGene00012015
Drosophila melanogaster	31185	FB:FBgn0004654
Homo sapiens	5226	HGNC:8891
Saccharomyces cerevisiae S288C	856589	SGD:S000001226
Saccharomyces cerevisiae S288C	853172	SGD:S000003488

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026