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phosphogluconate dehydrogenase (decarboxylating) GND2

Summary

Gene Symbol

GND2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853172

KEGG Gene ID

PubChem

853172

Alliance of Genome Resources

SGD:S000003488

Annotation

Keyword

Gluconate utilization
NADP
Oxidoreductase
Pentose shunt
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P53319

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
pentose-phosphate shunt	IEA
pentose-phosphate shunt, oxidative branch	RCA
pentose-phosphate shunt, oxidative branch	IMP
pentose-phosphate shunt, oxidative branch	IBA
pentose-phosphate shunt, oxidative branch	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

primary metabolic process [inference]

carbohydrate metabolic process [inference]

D-gluconate metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

D-gluconate metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process [inference]

NADPH regeneration [inference]

carbohydrate derivative metabolic process [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytosol	RCA
cytosol	IBA
plasma membrane	HDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
phosphogluconate dehydrogenase (decarboxylating) activity	RCA
phosphogluconate dehydrogenase (decarboxylating) activity	IMP
phosphogluconate dehydrogenase (decarboxylating) activity	IBA
phosphogluconate dehydrogenase (decarboxylating) activity	IEA
NADP binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

phosphogluconate dehydrogenase (decarboxylating) activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
plasma membrane	PMID:16622836

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	110208	MGI:97553
Rattus norvegicus	100360180	RGD:1583832
Caenorhabditis elegans	177971	WB:WBGene00012015
Drosophila melanogaster	31185	FB:FBgn0004654
Homo sapiens	5226	HGNC:8891