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oxoglutarate dehydrogenase

Summary

Gene Symbol

OGDH

Organism

Callithrix jacchus (white-tufted-ear marmoset)

External Links

NCBI Gene: 100386666
KEGG Gene ID: cjc:100386666
PubChem: 100386666

Annotation

Keyword

Isopeptide bond
Nucleus
Oxidoreductase
Reference proteome
Thiamine pyrophosphate
Transit peptide
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
U3FNY3	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
U3DCU9	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
F6XLN9	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
F6WZI4	2-oxoglutarate dehydrogenase, mitochondrial Alpha-ketoglutarate dehydrogenase Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
tricarboxylic acid cycle	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202
oxoglutarate dehydrogenase complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle enzyme complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

oxidoreductase complex [inference]

dihydrolipoyl dehydrogenase complex [inference]

oxoglutarate dehydrogenase complex

transferase complex [inference]

oxoglutarate dehydrogenase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oxoglutarate dehydrogenase (succinyl-transferring) activity	IEA	22301074 30032202
thiamine pyrophosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [inference]

oxoglutarate dehydrogenase (succinyl-transferring) activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dehydrogenase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
I: Lipid transport and metabolism

Displaying **all 5** entries
Gene Ontology
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
oxidoreductase activity
oxoglutarate dehydrogenase (succinyl-transferring) activity
thiamine pyrophosphate binding
tricarboxylic acid cycle

Displaying **all 7** entries
InterPro
2-oxoglutarate dehydrogenase E1 component, N-terminal domain
2-oxoglutarate dehydrogenase E1 component
Dehydrogenase, E1 component
Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily
Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
Thiamin diphosphate-binding fold
Transketolase-like, pyrimidine-binding domain

KEGG BRITE Database

Orthology

K00164

Name

2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

References

Rhea

RHEA:12188

H⁺ + 2-oxoglutarate

CO₂

Enzyme

1.2.4.2

PMID

Ortholog

Displaying entries **51 - 60** of **105** in total

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Species	Gene ID	Orthologous MAtrix
Cynoglossus semilaevis	103397981	CYNSE32359
Ursus maritimus	103674568	URSMA09948
Nannospalax galili	103734991	NANGA09187
Serinus canaria	103822661	SERCA19235
Rhinopithecus roxellana	104671151	RHIRO16957
Esox lucius	105014042	ESOLU39315
Esox lucius	105015304	ESOLU40406
Pteropus vampyrus	105308752	PTEVA04269
Macaca nemestrina	105494244	MACNE39313
Mandrillus leucophaeus	105541968	MANLE18792

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Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements