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MIRAGE

UDP-glucose 6-dehydrogenase

Summary

Gene Symbol

UGDH

Organism

Ochotona princeps (American pika)

External Links

NCBI Gene: 101521290
KEGG Gene ID: opi:101521290
PubChem: 101521290

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glycosaminoglycan biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
UDP-glucose 6-dehydrogenase activity	IEA	22301074 30032202
NAD binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

UDP-glucose 6-dehydrogenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

udp-glucose 6-dehydrogenase

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis

Displaying **all 5** entries
Gene Ontology
UDP-glucose 6-dehydrogenase activity
UDP-glucuronate biosynthetic process
glycosaminoglycan biosynthetic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity

Displaying **all 8** entries
InterPro
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
NAD(P)-binding domain superfamily
UDP-glucose 6-dehydrogenase, eukaryotic type
UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily
UDP-glucose/GDP-mannose dehydrogenase, C-terminal
UDP-glucose/GDP-mannose dehydrogenase, N-terminal
UDP-glucose/GDP-mannose dehydrogenase, dimerisation
UDP-glucose/GDP-mannose dehydrogenase

KEGG BRITE Database

Orthology

K00012

Name

UDPglucose 6-dehydrogenase [EC:1.1.1.22]

References

21961565

Ortholog

Displaying entries **31 - 40** of 79 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Octodon degus	101570209		OCTDE20812
Mustela putorius furo	101686502		MUSPF08519
Heterocephalus glaber	101726266		HETGA03962
Ficedula albicollis	101815332		FICAL12425
Melopsittacus undulatus	101868200		MELUD08053
Chrysemys picta bellii	101941904		CHRPI12191
Ictidomys tridecemlineatus	101959301		ICTTR02102
Chinchilla lanigera	102026048		CHILA11100
Macaca fascicularis	102116892		MACFA33643
Capra hircus	102171772		CAPHI26340

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 4, 2025