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BCAS2 pre-mRNA processing factor

Summary

Gene Symbol

BCAS2

Organism

Homo sapiens (human)

External Links

NCBI Gene

10286

PubChem

10286

Alliance of Genome Resources

HGNC:975

Annotation

Keyword

3D-structure
Acetylation
Coiled coil
Direct protein sequencing
Nucleus
Phosphoprotein
Reference proteome
Spliceosome
mRNA processing

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2R7W3
O75934	Breast carcinoma-amplified sequence 2 DNA amplified in mammary carcinoma 1 protein Spliceosome-associated protein SPF 27

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
RNA splicing, via transesterification reactions	TAS	9731529
alternative mRNA splicing, via spliceosome	IEA
mRNA splicing, via spliceosome	NAS	23742842
mRNA splicing, via spliceosome	IDA	28076346
ovarian follicle development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

protein metabolic process [inference]

protein catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

protein metabolic process [inference]

protein catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

spindle assembly

cell cycle process [inference]

spindle organization [inference]

spindle assembly

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oocyte development

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

alternative mRNA splicing, via spliceosome

cellular developmental process [inference]

cell development [inference]

germ cell development [inference]

oocyte development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

spindle assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

ovarian follicle development

germ cell development [inference]

oocyte development

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oocyte development

developmental process [inference]

developmental process involved in reproduction [inference]

ovarian follicle development

germ cell development [inference]

oocyte development

anatomical structure development [inference]

ovarian follicle development

cell development [inference]

germ cell development [inference]

oocyte development

cellular developmental process [inference]

cell development [inference]

germ cell development [inference]

oocyte development

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
Prp19 complex	IBA
Prp19 complex	IPI	20176811
nucleus	IDA	28076346
nucleoplasm	TAS
DNA replication factor A complex	IDA	24332808

GO Hierarchy

cellular component

protein-containing complex [inference]

Prp19 complex

nuclear protein-containing complex [inference]

DNA replication factor A complex

spliceosomal complex

U2-type spliceosomal complex [inference]

U2-type catalytic step 2 spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

catalytic complex [inference]

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

ribonucleoprotein complex [inference]

spliceosomal complex

U2-type spliceosomal complex [inference]

U2-type catalytic step 2 spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

cellular anatomical entity [inference]

nucleoplasm

microtubule organizing center [inference]

centrosome

nuclear body [inference]

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	20176811 20467437 22365833 25416956 27107012 28514442 30021884 31515488 32296183 32814053 33961781 35271311

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

pre-mRNA-splicing factor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
mRNA processing

Displaying 1 entry
InterPro
Pre-mRNA-splicing factor SPF27

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1612	breast cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	10286	Xenbase:XB-GENE-959514
Mus musculus	68183	Xenbase:XB-GENE-959514	MOUSE38218
Rattus norvegicus	295334		RATNO25367
Pan troglodytes	457143		PANTR21951
Canis lupus familiaris	475805		CANLF05269
Danio rerio	493614		DANRE42139
Bos taurus	507944		BOVIN26205
Macaca mulatta	695503		MACMU24576
Monodelphis domestica	100030739		MONDO15056
Sus scrofa	100154006		PIGXX24392