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isoleucyl-tRNA synthetase 1

Summary

Gene Symbol

Iars1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

105148

KEGG Gene ID

PubChem

105148

Alliance of Genome Resources

MGI:2145219

Annotation

Keyword

ATP-binding
Acetylation
Aminoacyl-tRNA synthetase
Cytoplasm
Phosphoprotein
Protein biosynthesis
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BU30	Isoleucyl-tRNA synthetase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
tRNA aminoacylation for protein translation	IEA
isoleucyl-tRNA aminoacylation	ISO
isoleucyl-tRNA aminoacylation	IDA
isoleucyl-tRNA aminoacylation	IBA
isoleucyl-tRNA aminoacylation	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

isoleucyl-tRNA aminoacylation

aminoacyl-tRNA metabolism involved in translational fidelity

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

isoleucyl-tRNA aminoacylation

aminoacyl-tRNA metabolism involved in translational fidelity

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

isoleucyl-tRNA aminoacylation

biological regulation [inference]

regulation of biological quality [inference]

regulation of translational fidelity [inference]

aminoacyl-tRNA metabolism involved in translational fidelity

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
cytoplasm	ISO
cytoplasm	IEA
cytosol	ISS
cytosol	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

aminoacyl-tRNA synthetase multienzyme complex

catalytic complex [inference]

aminoacyl-tRNA synthetase multienzyme complex

cellular anatomical structure [inference]

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
tRNA binding	IEA
nucleotide binding	IEA
aminoacyl-tRNA deacylase activity	IEA
aminoacyl-tRNA ligase activity	IEA
isoleucine-tRNA ligase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

aminoacyl-tRNA deacylase activity

ligase activity [inference]

ligase activity, forming carbon-oxygen bonds [inference]

aminoacyl-tRNA ligase activity

isoleucine-tRNA ligase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

aminoacyl-tRNA deacylase activity

aminoacyl-tRNA ligase activity

isoleucine-tRNA ligase activity

deacylase activity [inference]

aminoacyl-tRNA deacylase activity

binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

tRNA binding

protein binding [inference]

enzyme binding [inference]

GTPase binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Saccharomyces cerevisiae S288C	852202	SGD:S000000172

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