GlyCosmos Portal

Submissions

WNT inhibitory factor 1

Summary

Gene Symbol

WIF1

Organism

Homo sapiens (human)

External Links

NCBI Gene

11197

PubChem

11197

Alliance of Genome Resources

HGNC:18081

Annotation

Keyword

3D-structure
Developmental protein
Disulfide bond
EGF-like domain
Glycoprotein
Reference proteome
Repeat
Secreted
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Y5W5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	PMID
Wnt signaling pathway	IEA
negative regulation of Wnt signaling pathway	NAS	24431302
nodal signaling pathway
positive regulation of fat cell differentiation	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

activin receptor signaling pathway [inference]

nodal signaling pathway

Wnt signaling pathway

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

developmental process [inference]

anatomical structure development [inference]

blood vessel development

animal organ development [inference]

heart development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of fat cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of fat cell differentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of fat cell differentiation

regulation of fat cell differentiation [inference]

positive regulation of fat cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of fat cell differentiation

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

activin receptor signaling pathway [inference]

nodal signaling pathway

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of fat cell differentiation

regulation of fat cell differentiation [inference]

positive regulation of fat cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of fat cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IBA
cell surface	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IBA
protein binding	IPI	19188438 21743455 22986341 25416956 26342861 32296183
Wnt-protein binding	NAS	24431302
nodal binding
activin receptor binding

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

receptor serine/threonine kinase binding [inference]

transmembrane receptor protein serine/threonine kinase binding [inference]

activin receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

HHIP

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 3** entries
InterPro
Glucose/Sorbosone dehydrogenase
Six-bladed beta-propeller, TolB-like
Soluble quinoprotein glucose/sorbosone dehydrogenase

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:4450	renal cell carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 64 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	11197	Xenbase:XB-GENE-486515
Mus musculus	24117	Xenbase:XB-GENE-486515	MOUSE00522
Danio rerio	30476	Xenbase:XB-GENE-486515	DANRE34094
Xenopus tropicalis	31617	Xenbase:XB-GENE-486515
Rattus norvegicus	114557		RATNO37898
Xenopus tropicalis	399375	Xenbase:XB-GENE-486515
Pan troglodytes	467056		PANTR05366
Canis lupus familiaris	481148		CANLF01388
Bos taurus	533672		BOVIN29490
Equus caballus	100057139		HORSE36678