GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

annexin A5

Summary

Gene Symbol

Anxa5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

11747

KEGG Gene ID

PubChem

11747

Alliance of Genome Resources

MGI:106008

Annotation

Keyword

Acetylation
Annexin
Blood coagulation
Calcium/phospholipid-binding
Direct protein sequencing
Isopeptide bond
Phosphoprotein
Reference proteome
Repeat
S-nitrosylation
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P48036	Anchorin CII Annexin V Annexin-5 Calphobindin I Endonexin II Lipocortin V Placental anticoagulant protein 4 Placental anticoagulant protein I Thromboplastin inhibitor Vascular anticoagulant-alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
blood coagulation
negative regulation of blood coagulation	ISO
positive regulation of apoptotic process	ISO
negative regulation of coagulation	IEA
response to calcium ion	ISO

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

multicellular organismal process [inference]

coagulation [inference]

blood coagulation

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to peptide hormone [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to gonadotropin-releasing hormone [inference]

cellular response to gonadotropin-releasing hormone

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to peptide hormone [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to gonadotropin-releasing hormone [inference]

cellular response to gonadotropin-releasing hormone

response to metal ion [inference]

response to calcium ion

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to nitrogen compound [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to gonadotropin-releasing hormone [inference]

cellular response to gonadotropin-releasing hormone

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

response to gonadotropin-releasing hormone [inference]

cellular response to gonadotropin-releasing hormone

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

cellular response to nitrogen compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

cellular response to oxygen-containing compound [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to gonadotropin-releasing hormone

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of peptide hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

regulation of transport [inference]

regulation of secretion [inference]

regulation of peptide secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of peptide hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of peptide hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of peptide hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cilium-dependent cell motility [inference]

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation

negative regulation of blood coagulation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of peptide hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of cilium movement [inference]

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of peptide hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

negative regulation of protein secretion [inference]

negative regulation of prolactin secretion

regulation of cell motility [inference]

regulation of cilium-dependent cell motility [inference]

regulation of cilium movement involved in cell motility [inference]

regulation of flagellated sperm motility

regulation of multicellular organismal process [inference]

regulation of coagulation [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation

negative regulation of coagulation

negative regulation of blood coagulation

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation

negative regulation of blood coagulation

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation

regulation of reproductive process [inference]

regulation of flagellated sperm motility

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of peptide hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of prolactin secretion

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

regulation of hemostasis [inference]

regulation of blood coagulation [inference]

negative regulation of blood coagulation

negative regulation of hemostasis [inference]

negative regulation of blood coagulation

Displaying entries **1 - 5** of 18 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
extracellular region	ISO
obsolete extracellular space
cytoplasm	IBA
synaptic vesicle	ISO
external side of plasma membrane	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane [inference]

sarcolemma

organelle membrane [inference]

vesicle membrane

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

Z disc

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

cell-cell contact zone [inference]

intercalated disc

external encapsulating structure [inference]

extracellular matrix

cell projection

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

blood microparticle [inference]

endothelial microparticle

side of membrane [inference]

external side of plasma membrane

presynapse [inference]

axon terminus

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
phosphatidylserine binding	IDA
phosphatidylserine binding	IBA
P-type calcium transporter activity	ISO
calcium ion binding	IEA
protein binding	IPI

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type calcium transporter activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

P-type calcium transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type calcium transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type calcium transporter activity

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type calcium transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type calcium transporter activity

binding [inference]

protein binding

signaling receptor binding [inference]

receptor tyrosine kinase binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

identical protein binding

lipid binding [inference]

phospholipid binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

phosphatidylserine binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

hormone binding [inference]

peptide hormone binding

modified amino acid binding [inference]

phosphatidylserine binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type calcium transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type calcium transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Annexin

Functional Category

K: Transcription
N: Cell motility
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
calcium ion binding
calcium-dependent phospholipid binding

Displaying **all 4** entries
InterPro
Annexin repeat, conserved site
Annexin repeat
Annexin superfamily
Annexin

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	308	HGNC:543

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: [email protected]

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026