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Guidelines

MIRAGE

bone morphogenetic protein 5

Summary

Gene Symbol

Bmp5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12160

KEGG Gene ID

PubChem

12160

Alliance of Genome Resources

MGI:88181

Annotation

Keyword

Alternative splicing
Chondrogenesis
Cleavage on pair of basic residues
Cytokine
Developmental protein
Differentiation
Disulfide bond
Glycoprotein
Growth factor
Osteogenesis
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UXE6
P49003

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 45 in total

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GO Term	Evidence Code	PMID
skeletal system development	IMP
ossification
endocardial cushion formation	IGI
type B pancreatic cell development	ISO
type B pancreatic cell development	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

chorio-allantoic fusion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

cellular developmental process [inference]

cell differentiation

cell development [inference]

epithelial cell development [inference]

type B pancreatic cell development

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

male genitalia development

multicellular organismal process [inference]

developmental process

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

male genitalia development

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

pericardium morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of an epithelial sheet [inference]

pericardium morphogenesis

cardiac septum morphogenesis

trabecula morphogenesis [inference]

heart trabecula morphogenesis

anatomical structure formation involved in morphogenesis [inference]

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

striated muscle tissue development [inference]

cardiac muscle tissue development

hindbrain development

cell development [inference]

epithelial cell development [inference]

type B pancreatic cell development

animal organ development [inference]

sensory organ development [inference]

ear development

heart development

genitalia development [inference]

male genitalia development

cartilage development

reproductive structure development [inference]

genitalia development [inference]

male genitalia development

system development [inference]

reproductive system development [inference]

male genitalia development

head development [inference]

anterior head development

extraembryonic membrane development [inference]

allantois development

cellular developmental process [inference]

cell differentiation

cell development [inference]

epithelial cell development [inference]

type B pancreatic cell development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of insulin-like growth factor receptor signaling pathway [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of epithelial cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of developmental process [inference]

positive regulation of dendrite development

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of alcohol biosynthetic process [inference]

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of small molecule metabolic process [inference]

negative regulation of alcohol biosynthetic process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of insulin-like growth factor receptor signaling pathway [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of developmental process [inference]

regulation of dendrite development [inference]

positive regulation of dendrite development

positive regulation of developmental process [inference]

positive regulation of dendrite development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of insulin-like growth factor receptor signaling pathway [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of alcohol biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of ketone biosynthetic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of alcohol biosynthetic process [inference]

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of alcohol biosynthetic process [inference]

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of small molecule metabolic process [inference]

negative regulation of alcohol biosynthetic process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of ketone metabolic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone metabolic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

regulation of hormone metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone metabolic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of small molecule metabolic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone metabolic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of small molecule metabolic process [inference]

negative regulation of alcohol biosynthetic process [inference]

regulation of alcohol biosynthetic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of alcohol biosynthetic process [inference]

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of steroid metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone metabolic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of epithelial cell proliferation

negative regulation of cell population proliferation

regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of epithelial cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of alcohol biosynthetic process [inference]

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

negative regulation of small molecule metabolic process [inference]

negative regulation of alcohol biosynthetic process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of dendrite development [inference]

positive regulation of dendrite development

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone metabolic process [inference]

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of cortisol biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

regulation of aldosterone biosynthetic process [inference]

negative regulation of aldosterone biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process [inference]

negative regulation of cortisol biosynthetic process

negative regulation of aldosterone biosynthetic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space
vesicle	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

organelle [inference]

membrane-bounded organelle [inference]

vesicle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytokine activity	IBA
protein binding	IPI
growth factor activity	IEA
BMP receptor binding	ISO
BMP receptor binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

receptor serine/threonine kinase binding [inference]

transmembrane receptor protein serine/threonine kinase binding [inference]

BMP receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Bone morphogenetic protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cytokine activity
growth factor activity

Displaying **all 5** entries
InterPro
Cystine-knot cytokine
TGF-beta, propeptide
Transforming growth factor beta, conserved site
Transforming growth factor-beta, C-terminal
Transforming growth factor-beta-related

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060306	Meier-Gorlin syndrome	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	179068	WB:WBGene00000936
Drosophila melanogaster	46000	FB:FBgn0005590
Drosophila melanogaster	37778	FB:FBgn0024234
Homo sapiens	653	HGNC:1072

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026