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deleted in malignant brain tumors 1

Summary

Gene Symbol

Dmbt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12945

PubChem

12945

Alliance of Genome Resources

MGI:106210

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
Developmental protein
Differentiation
Direct protein sequencing
Disulfide bond
Glycoprotein
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q60997	Apactin CRP-ductin Glycoprotein 300 Hensin Mucin-like glycoprotein Vomeroglandin p80
A0A140LI59	Hensin
E9QPG8	Hensin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
blastocyst development	IMP	15452149
inner cell mass cell proliferation	IDA	15452149
columnar/cuboidal epithelial cell differentiation	IDA	15452149
receptor-mediated endocytosis	ISO
defense response	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

antimicrobial humoral immune response mediated by antimicrobial peptide

cellular process [inference]

cell population proliferation [inference]

inner cell mass cell proliferation

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cellular developmental process [inference]

cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

developmental process [inference]

anatomical structure development [inference]

blastocyst development

cellular developmental process [inference]

cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

defense response to other organism [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

response to stimulus [inference]

response to stress [inference]

defense response

defense response to other organism [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

defense response to other organism [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

defense response to other organism [inference]

antimicrobial humoral response [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

antimicrobial humoral immune response mediated by antimicrobial peptide

defense response to bacterium [inference]

antibacterial humoral response [inference]

induction of bacterial agglutination

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial cell differentiation

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	ISO
extracellular space	IBA
intracellular anatomical structure	IDA	15452149
cytoplasm	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

zymogen granule membrane

bounding membrane of organelle [inference]

transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

secretory granule membrane [inference]

zymogen granule membrane

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
lipopolysaccharide binding	ISO
DNA binding	ISO
scavenger receptor activity	ISO
extracellular matrix structural constituent	RCA	22159717 28071719
protein binding	IPI	12884308

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding

enzyme binding [inference]

zymogen binding

lipid binding [inference]

lipopolysaccharide binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

heparan sulfate binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

glycosaminoglycan binding [inference]

heparan sulfate binding

lipoteichoic acid binding

sulfur compound binding [inference]

heparan sulfate binding

cargo receptor activity [inference]

scavenger receptor activity

molecular transducer activity [inference]

signaling receptor activity [inference]

pattern recognition receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

deleted in malignant brain tumors 1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
serine-type endopeptidase activity

Displaying **all 3** entries
InterPro
SRCR domain
SRCR-like domain superfamily
SRCR-like domain

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1755	Xenbase:XB-GENE-6000361	HUMAN03254
Xenopus tropicalis	12945	Xenbase:XB-GENE-6000361
Rattus norvegicus	170568	Xenbase:XB-GENE-6000361	RATNO17937
Pan troglodytes	466221		PANTR01724
Pan paniscus	100975652		PANPA05654