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colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

Summary

Gene Symbol

Csf2ra

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

12982

PubChem

12982

Alliance of Genome Resources

MGI:1339754

Annotation

Keyword

Alternative splicing
Cell membrane
Glycoprotein
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q00941

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway via JAK-STAT	ISO	http://purl.obolibrary.org/obo/go/references/0000119
granulocyte-macrophage colony-stimulating factor signaling pathway	ISO	http://purl.obolibrary.org/obo/go/references/0000119
granulocyte colony-stimulating factor signaling pathway	IEA
positive regulation of leukocyte proliferation	ISO	http://purl.obolibrary.org/obo/go/references/0000119
cellular response to granulocyte macrophage colony-stimulating factor stimulus	IDA	17694571

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

response to stimulus [inference]

response to chemical [inference]

response to peptide [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to granulocyte macrophage colony-stimulating factor stimulus

response to granulocyte macrophage colony-stimulating factor [inference]

cellular response to granulocyte macrophage colony-stimulating factor stimulus

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

regulation of leukocyte proliferation [inference]

positive regulation of leukocyte proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	EXP	17694571
plasma membrane	IDA	17694571
plasma membrane	IEA	http://purl.obolibrary.org/obo/go/references/0000044
membrane	IEA
granulocyte macrophage colony-stimulating factor receptor complex	ISO	http://purl.obolibrary.org/obo/go/references/0000119

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

cellular anatomical structure [inference]

membrane

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytokine receptor activity	IEA	http://purl.obolibrary.org/obo/go/references/0000002
granulocyte colony-stimulating factor receptor activity	IDA	17694571
granulocyte colony-stimulating factor binding	IDA	17694571

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

granulocyte colony-stimulating factor binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

granulocyte colony-stimulating factor receptor activity

immune receptor activity [inference]

cytokine receptor activity

granulocyte colony-stimulating factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

granulocyte-macrophage colony-stimulating factor receptor subunit alpha

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cytokine-mediated signaling pathway

Displaying **all 4** entries
InterPro
Fibronectin type III superfamily
Immunoglobulin-like fold
Short hematopoietin receptor, family 2, conserved site
Type I cytokine receptor, cytokine-binding domain