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Granulocyte-macrophage colony-stimulating factor receptor subunit alpha

Summary

UniProt ID

Q00941

Gene Symbol

Csf2ra
Csfgmra

Gene ID

12982

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003848
Re-Glyco: Q00941

Annotation

Keyword: Alternative splicing Cell membrane Glycoprotein Receptor Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
cell surface receptor signaling pathway via JAK-STAT	ISO	GO_REF
granulocyte-macrophage colony-stimulating factor signaling pathway	ISO	GO_REF
positive regulation of leukocyte proliferation	ISO	GO_REF
cellular response to granulocyte macrophage colony-stimulating factor stimulus	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

granulocyte-macrophage colony-stimulating factor signaling pathway

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

response to stimulus [inference]

response to chemical [inference]

response to peptide [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to granulocyte macrophage colony-stimulating factor stimulus

response to granulocyte macrophage colony-stimulating factor [inference]

cellular response to granulocyte macrophage colony-stimulating factor stimulus

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

granulocyte-macrophage colony-stimulating factor signaling pathway

cell surface receptor signaling pathway via STAT [inference]

cell surface receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

regulation of leukocyte proliferation [inference]

positive regulation of leukocyte proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation

Displaying **all 4** entries
GO Term	Evidence Code	Reference
plasma membrane	EXP	PMID
plasma membrane	IDA	PMID
plasma membrane	IEA	GO_REF
granulocyte macrophage colony-stimulating factor receptor complex	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

granulocyte macrophage colony-stimulating factor receptor complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
cytokine receptor activity	IEA	GO_REF
granulocyte colony-stimulating factor receptor activity	IDA	PMID
granulocyte colony-stimulating factor binding	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

granulocyte colony-stimulating factor binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

granulocyte colony-stimulating factor receptor activity

immune receptor activity [inference]

cytokine receptor activity

granulocyte colony-stimulating factor receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTSSHAMNITPLAQLALLFSTLLLPGTQALLAPTTPDAGSALNLTFDPWTRTLTWACDTAAGNVTVTSCTVTSREAGIHRRVSPFGCRCWFRRMMALHHGVTLDVNGTVGGAAAHWRLSFVNEGAAGSGAENLTCEIRAARFLSCAWREGPAAPADVRYSLRVLNSTGHDVARCMADPGDDVITQCIANDLSLLGSEAYLVVTGRSGAGPVRFLDDVVATKALERLGPPRDVTASCNSSHCTVSWAPPSTWASLTARDFQFEVQWQSAEPGSTPRKVLVVEETRLAFPSPAPHGGHKVKVRAGDTRMKHWGEWSPAHPLEAEDTRVPGALLYAVTACAVLLCALALGVTCRRFEVTRRLFPPIPGIRDKVSDDVRVNPETLRKDLLQP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
43	N-linked (GlcNAc...) asparagine	UniProt
63	N-linked (GlcNAc...) asparagine	UniProt
106	N-linked (GlcNAc...) asparagine	UniProt
132	N-linked (GlcNAc...) asparagine	UniProt
165	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
237	N-linked (GlcNAc...) asparagine	UniProt