GlyCosmos Portal

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versican

Summary

Gene Symbol

Vcan

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

13003

PubChem

13003

Alliance of Genome Resources

MGI:102889

Annotation

Keyword

Disulfide bond
EGF-like domain
Extracellular matrix
Hyaluronic acid
Immunoglobulin domain
Lectin
Proteoglycan
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Sushi

Proteins

Displaying **all 5** entries
UniProt	Protein Name
E9PYH0	Chondroitin sulfate proteoglycan core protein 2 Large fibroblast proteoglycan PG-M
G3XA35	Chondroitin sulfate proteoglycan core protein 2 Large fibroblast proteoglycan PG-M
E9QMK3	Chondroitin sulfate proteoglycan core protein 2 Large fibroblast proteoglycan PG-M
Q8BS97
E9QMK2	Chondroitin sulfate proteoglycan core protein 2 Large fibroblast proteoglycan PG-M

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
skeletal system development	IBA
ureteric bud development	IEP	16545622
cell adhesion	IEA
central nervous system development	IBA
heart development	IMP	9758703

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell motility [inference]

cell migration [inference]

glial cell migration

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

kidney epithelium development [inference]

mesonephric epithelium development [inference]

mesonephric tubule development [inference]

ureteric bud development

tube development [inference]

mesonephric tubule development [inference]

ureteric bud development

animal organ development [inference]

heart development

system development [inference]

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment	IEA
extracellular region	ISS
extracellular region	ISO
extracellular space	IBA
cell surface	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

interphotoreceptor matrix

perisynaptic extracellular matrix [inference]

perineuronal net

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GO Term	Evidence Code	PMID
calcium ion binding	IEA
hyaluronic acid binding	IEA
protein tyrosine phosphatase activator activity
protein phosphatase binding	IPI	21976490
extracellular matrix structural constituent conferring compression resistance	RCA	22159717

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent [inference]

extracellular matrix structural constituent conferring compression resistance

binding [inference]

protein binding [inference]

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

hyaluronic acid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

phosphatase activator activity [inference]

protein phosphatase activator activity [inference]

protein tyrosine phosphatase activator activity

phosphatase regulator activity [inference]

phosphatase activator activity [inference]

protein phosphatase activator activity [inference]

protein tyrosine phosphatase activator activity

protein phosphatase regulator activity [inference]

protein phosphatase activator activity [inference]

protein tyrosine phosphatase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

phosphatase activator activity [inference]

protein phosphatase activator activity [inference]

protein tyrosine phosphatase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Versican core protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
calcium ion binding
central nervous system development
hyaluronic acid binding
positive regulation of neuroblast proliferation
skeletal system development

Displaying **all 7** entries
InterPro
C-type lectin fold
C-type lectin-like/link domain superfamily
C-type lectin-like
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
EGF-type aspartate/asparagine hydroxylation site

Ortholog

Displaying entries **1 - 10** of 55 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1462	Xenbase:XB-GENE-922302	HUMAN79922
Xenopus tropicalis	13003	Xenbase:XB-GENE-922302
Rattus norvegicus	114122	Xenbase:XB-GENE-922302	RATNO23452
Bos taurus	282662		BOVIN33927
Sus scrofa	397328		PIGXX19385
Pan troglodytes	461766		PANTR35167
Canis lupus familiaris	488922		CANLF11899
Macaca mulatta	712365		MACMU38910
Oryctolagus cuniculus	100008666		RABIT01778
Equus caballus	100065275		HORSE08615