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fucosyltransferase 4

Summary

Gene Symbol

Fut4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14345

KEGG Gene ID

mmu:14345

PubChem

14345

Alliance of Genome Resources

MGI:95594

Annotation

Keyword

Alternative splicing
Glycoprotein
Glycosyltransferase
Golgi apparatus
Inflammatory response
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q544B8
Q11127	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Fucosyltransferase 4 Fucosyltransferase IV Galactoside 3-L-fucosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
protein N-linked glycosylation	ISS
protein N-linked glycosylation	ISO
protein O-linked glycosylation	ISS
protein O-linked glycosylation	ISO
glycosphingolipid biosynthetic process	ISS

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

Lewis x epitope biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

lipid metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

Lewis x epitope biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosphingolipid biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
trans-Golgi network	ISS
trans-Golgi network	ISO
trans-Golgi network	IEA
cell surface	IDA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane

organelle membrane [inference]

Golgi cisterna membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

cell periphery

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
fucosyltransferase activity	IEA
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	ISS
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	ISO
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	EXP
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity

alpha-(1->3)-fucosyltransferase activity

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07632

Name

galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-]

References

Reactions

Displaying entries **1 - 10** of 11 in total

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KEGG Reaction	Enzyme	Acceptor	Product
R06038	2.4.1.- 2.4.1.152 2.4.1.65	G84034JH	G76439VL
R06230	2.4.1.- 2.4.1.152 2.4.1.65	G84034JH	G65223RT
R06221	2.4.1.- 2.4.1.152 2.4.1.65	G76439VL	G91560NT
R06222	2.4.1.- 2.4.1.152 2.4.1.65	G00851XQ	G52160KJ
R06075	2.4.1.- 2.4.1.65	G01767JJ	G96401FK
R06025	2.4.1.- 2.4.1.152 2.4.1.65	G58896AZ	G72002FC
R06227	2.4.1.- 2.4.1.152 2.4.1.65	G07075ZE	G03564IA
R06076	2.4.1.- 2.4.1.152 2.4.1.65	G66427ZQ	G07075ZE
R06224	2.4.1.- 2.4.1.152 2.4.1.65	G52160KJ	G20180GO
R06095	2.4.1.- 2.4.1.152 2.4.1.65	G13636IT	G89659QV

Rhea

RHEA:14257

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

a β-D-galactosyl-(1→4)-[α-L-fucosyl-(1→3)]-N-acetyl-β-D-glucosaminyl derivative + H⁺ + GDP

Enzyme

2.4.1.152

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000228
Gene Name: fucosyltransferase 4

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	60670	RGD:619954
Caenorhabditis elegans	3565968	WB:WBGene00043986
Caenorhabditis elegans	187342	WB:WBGene00001507
Caenorhabditis elegans	173958	WB:WBGene00006402
Caenorhabditis elegans	188084	WB:WBGene00020222
Drosophila melanogaster	3355171	FB:FBgn0044872
Drosophila melanogaster	39653	FB:FBgn0036485
Homo sapiens	2526	HGNC:4015
Xenopus tropicalis	447974	Xenbase:XB-GENE-979293