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MIRAGE
G58896AZ

Summary
GlyTouCan ID
G58896AZ
IUPAC Condensed
Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-
Motifs
Paragloboside
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
707.25
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
CarbBank
3D Structures
GLYCAM
DGalpb1-4DGlcpNAcb1-3DGalpb1-4DGlcpb1-OH
GlycoShape
G58896AZ
Displaying 1 entry
Archetype α β
G00070MO
G14632ZD
G58896AZ
Organisms
Displaying entries 1 - 5 of 13 in total
Organisms Evidence
Ovis aries (sheep)
Cricetulus griseus (Chinese hamster)
Mus musculus (house mouse)
Bos taurus (domestic cattle)
Gallus gallus (chicken)
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GAL2 CMP-Neu5Ac
G58896AZ
Free
G83513YI
Free
B4GALT3 UDP-Gal
G06239NA
R
G58896AZ
R
B4GALT4 UDP-Gal
G06239NA
Cer
G58896AZ
Cer
B4GALT3 UDP-Gal
G06239NA
Cer
G58896AZ
Cer
Displaying entries 1 - 5 of 17 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST3GAL6 CMP-Neu5Ac
G58896AZ
ceramide
G01767JJ
ceramide
ST6GAL2 CMP-Neu5Ac
G58896AZ
Free
G83513YI
Free
B4GALT3 UDP-Gal
G06239NA
R
G58896AZ
R
B4GALT4 UDP-Gal
G06239NA
G58896AZ
B4GALT4 UDP-Gal
G06239NA
Cer
G58896AZ
Cer
Displaying entries 1 - 5 of 14 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GALNAC5 CMP-Neu5Ac
G58896AZ
ceramide
ST6GALNAC6 CMP-Neu5Ac
G58896AZ
ceramide
ST3GAL1 CMP-Neu5Ac
G58896AZ
free
FUT7 GDP-Fuc
G58896AZ
Free
B4GALT3 UDP-Gal
G58896AZ
Cer
KEGG BRITE Database
KEGG ID
Enzyme
References
Reactions
Displaying all 8 entries
KEGG Reaction Enzyme Acceptor Product
R06024
R06026
R05977
R05978
R06025
R11378
R11375
R05975
GlycoEpitope
Epitope ID
EP0075
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:b-dglc-HEX-1:5
4s:n-acetyl
5b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+1)3d
3:3d(2+1)4n
4:3o(4+1)5d
WURCS
WURCS=2.0/3,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3-2/a4-b1_b3-c1_c4-d1
Literature
Displaying entries 1 - 10 of 57 in total
PubMed ID Title First Author Publication Date Source
28000747 Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8 Bohari MH 2016 Dec 21
  • PubChem
26420502 Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus Hu L 2015 Sep 30
  • PubChem
26077389 Structural characterization of human galectin‐4 C‐terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens Bum-Erdene K 2015 Jul 14
  • PubChem
24326249 Galectin-3 Interactions with Glycosphingolipids Collins PM 2014 Apr 03
  • PubChem
21984010 The immune response to group B streptococcus type III capsular polysaccharide is directed to the -Glc-GlcNAc-Gal- backbone epitope Safari D 2011 Oct 08
  • PubChem
20686025 Crystallographic Structure of Porcine Adenovirus Type 4 Fiber Head and Galectin Domains Guardado-Calvo P 2010 Oct 15
  • PubChem
18678667 Identification of the Smallest Structure Capable of Evoking Opsonophagocytic Antibodies against Streptococcus pneumoniae Type 14 Safari D 2008 Oct
  • BCSDB
  • GlyGen
  • PubChem
17101655 Affinity-Purified Human Immunoglobulin G That Binds a Lacto-N-Neotetraose-Dependent Lipooligosaccharide Structure Is Bactericidal for Serogroup BNeisseria meningitidis Estabrook MM 2007 Feb
  • PubChem
17372007 Factor H Binding and Function in Sialylated Pathogenic Neisseriae is Influenced by Gonococcal, but Not Meningococcal, Porin Madico G 2007 Apr 01
  • PubChem
16441441 Neisseria meningitidis expressing lgtB lipopolysaccharide targets DC-SIGN and modulates dendritic cell function Steeghs L 2006 Feb
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids.
  • Togayachi A
  • Akashima T
  • Ookubo R
  • Kudo T
  • Nishihara S
  • Iwasaki H
  • Natsume A
  • Mio H
  • Inokuchi J
  • Irimura T
  • Sasaki K
  • Narimatsu H
 J Biol Chem 2001 Jun 22 11283017
Molecular cloning and characterization of a human beta-Gal-3'-sulfotransferase that acts on both type 1 and type 2 (Gal beta 1-3/1-4GlcNAc-R) oligosaccharides.
  • Honke K
  • Tsuda M
  • Koyota S
  • Wada Y
  • Iida-Tanaka N
  • Ishizuka I
  • Nakayama J
  • Taniguchi N
 J Biol Chem 2001 Jan 5 11029462
Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis.
  • Henion TR
  • Zhou D
  • Wolfer DP
  • Jungalwala FB
  • Hennet T
 J Biol Chem 2001 Aug 10 11384981
Cloning and expression of a novel galactoside beta1, 3-glucuronyltransferase involved in the biosynthesis of HNK-1 epitope.
  • Shimoda Y
  • Tajima Y
  • Nagase T
  • Harii K
  • Osumi N
  • Sanai Y
 J Biol Chem 1999 Jun 11 10358066
Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids.
  • Okajima T
  • Fukumoto S
  • Miyazaki H
  • Ishida H
  • Kiso M
  • Furukawa K
  • Urano T
  • Furukawa K
 J Biol Chem 1999 Apr 23 10206952
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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