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ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

Summary

Gene Symbol

ST6GALNAC6

Aliases

ST6GALNACVI

Organism

Homo sapiens (human)

External Links

NCBI Gene

30815

GGDB ID

gg061

HGNC

23364

mRNA

NM_013443

map

9q34.11

Protein

NP_038471

OMIM

610135

KEGG Gene ID

hsa:30815

PubChem

30815

Alliance of Genome Resources

HGNC:23364

JoGo

ST6GALNAC6

TogoVar

ST6GALNAC6

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Proteomics identification
Reference proteome
Sialic acid
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
B4DU80
F6SGE3
Q969X2	GalNAc alpha-2,6-sialyltransferase VI ST6GalNAc VI Sialyltransferase 7F
A0A0S2Z5G9	GalNAc alpha-2,6-sialyltransferase VI ST6GalNAc VI Sialyltransferase 7F

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
ganglioside biosynthetic process	ISS
ganglioside biosynthetic process	IBA
lipid metabolic process
ceramide metabolic process	IEA
glycosylceramide metabolic process	IDA

GO Hierarchy

biological process

cellular process [inference]

cell recognition [inference]

cell-cell recognition

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process

glycoprotein biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process

glycoprotein biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IEA
cytoplasm	ISS
cytoplasm	IEA
plasma membrane	NAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	ISS
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	TAS
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IBA
protein binding	IPI
sialyltransferase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000160408

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg061

Gene Symbol

ST6GALNAC6

Reactions

Displaying **all 2** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Reference
CMP-Neu5Ac	G58896AZ	ceramide	12668675
CMP-Neu5Ac	G00049MO	ceramide	12668675

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Mus musculus	NP_058669	NM_016973
Rattus norvegicus	CAG26710	AJ646881

KEGG BRITE Database

Orthology

K03376

Name

N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7F) [EC:2.4.3.-]

References

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05945		G46677TE	G02149VR
R05959	2.4.3.7	G03277YI	G45714BQ
R05951		G40183QN	G54733XO

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006678
Gene Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	50935	MGI:1355316
Rattus norvegicus	407765	RGD:1303196
Danio rerio	407715	ZFIN:ZDB-GENE-060322-7
Xenopus laevis	108705031	Xenbase:XB-GENE-17333242
Xenopus laevis	108699976	Xenbase:XB-GENE-6486749
Xenopus tropicalis	100329192	Xenbase:XB-GENE-1012034

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements