G00049MO

Summary
GlyTouCan ID
G00049MO
IUPAC Condensed
Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-
Motifs
Lactotriaosylceramide Lc3 Type 1 LN
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
707.25
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoShape
Organisms
GlycoGene Database (GGDB)
Displaying entries 1 - 5 of 6 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
B3GALT2 UDP-Gal
G06239NA
Cer
G00049MO
Cer
B3GALT1 UDP-Gal
G06239NA
Cer
G00049MO
Cer
B3GALT5 UDP-Gal
G06239NA
Cer
G00049MO
Cer
B3GNT2 UDP-GlcNAc
G00049MO
R
G97033IB
R
B3GNT3 UDP-GlcNAc
G00049MO
PA
G97033IB
PA
Displaying entries 1 - 5 of 13 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GAL2 CMP-Neu5Ac
G00049MO
free
ST3GAL6 CMP-Neu5Ac
G00049MO
ceramide
ST6GALNAC6 CMP-Neu5Ac
G00049MO
ceramide
ST3GAL4 CMP-Neu5Ac
G00049MO
free
ST6GAL1 CMP-Neu5Ac
G00049MO
free
GlycoEpitope
Epitope ID
EP0114
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:b-dglc-HEX-1:5
4s:n-acetyl
5b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+1)3d
3:3d(2+1)4n
4:3o(3+1)5d
WURCS
WURCS=2.0/3,4,3/[a2122h-1b_1-5][a2112h-1b_1-5][a2122h-1b_1-5_2*NCC/3=O]/1-2-3-2/a4-b1_b3-c1_c3-d1
Literature
Displaying entries 1 - 10 of 165 in total
PubMed ID Title First Author Publication Date Source
39581422 Highly efficient production of lacto-N-tetraose in plasmid-free Escherichia coli through chromosomal integration of multicopy key glycosyltransferase genes Qian Q 2025 Jan
  • PubChem
39223086 Enzymatic Synthesis of Disialyllacto‐N‐Tetraose (DSLNT) and Related Human Milk Oligosaccharides Reveals Broad Siglec Recognition of the Atypical Neu5Acα2‐6GlcNAc Motif Bao S 2024 Oct 24
  • PubChem
39315793 Selective human milk oligosaccharide utilization by members of the Bifidobacterium pseudocatenulatum taxon Sanchez-Gallardo R 2024 Oct 23
  • PubChem
39508523 Biosynthesis of Sialyllacto-N-tetraose c in Engineered Escherichia coli Li C 2024 Nov 07
  • PubChem
39265897 Crystal structure and structure-guided tunnel engineering in a bacterial β-1,4-galactosyltransferase Luo G 2024 Nov
  • PubChem
38520358 Implementation of a Quorum-Sensing System for Highly Efficient Biosynthesis of Lacto-N-neotetraose in Engineered Escherichia coli MG1655 Tao M 2024 Mar 23
  • PubChem
38316330 Pre-clinical safety assessment of biotechnologically produced lacto-N-tetraose (LNT) van der Woude H 2024 Mar
  • PubChem
38503081 Characterization and application of active human α2,6-sialyltransferases ST6GalNAc V and ST6GalNAc VI recombined in Escherichia coli Pei C 2024 Jun
  • PubChem
38275134 High-Yield Synthesis of Lacto-N-Neotetraose from Glycerol and Glucose in Engineered Escherichia coli Liao Y 2024 Jan 26
  • PubChem
38364314 Microbial Synthesis of Lacto-N-fucopentaose I with High Titer and Purity by Screening of Specific Glycosyltransferase and Elimination of Residual Lacto-N-triose II and Lacto-N-tetraose Zhu Y 2024 Feb 16
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 8 in total
Title Authors Source Publication Date PubMed ID
Carbohydrate recognition by enterohemorrhagic Escherichia coli: characterization of a novel glycosphingolipid from cat small intestine.
  • Teneberg S
  • Angström J
  • Ljungh A
Glycobiology 2004 Feb 14576169
Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides.
  • Tsuchida A
  • Okajima T
  • Furukawa K
  • Ando T
  • Ishida H
  • Yoshida A
  • Nakamura Y
  • Kannagi R
  • Kiso M
  • Furukawa K
J Biol Chem 2003 Jun 20 12668675
Lactotetraosylceramide, a novel glycosphingolipid receptor for Helicobacter pylori, present in human gastric epithelium.
  • Teneberg S
  • Leonardsson I
  • Karlsson H
  • Jovall PA
  • Angstrom J
  • Danielsson D
  • Naslund I
  • Ljungh A
  • Wadstrom T
  • Karlsson KA
J Biol Chem 2002 May 31 11914375
A novel ganglioside isolated from renal cell carcinoma.
  • Ito A
  • Levery SB
  • Saito S
  • Satoh M
  • Hakomori S
J Biol Chem 2001 May 18 11278988
Monoclonal antibody (5F3) defining renal cell carcinoma-associated antigen disialosyl globopentaosylceramide (V3NeuAcIV6NeuAcGb5), and distribution pattern of the antigen in tumor and normal tissues.
  • Ito A
  • Saito S
  • Masuko T
  • Oh-Eda M
  • Matsuura T
  • Satoh M
  • Nejad FM
  • Enomoto T
  • Orikasa S
  • Hakomori SI
Glycoconj J 2001 Jun 12084983

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025