G40183QN

Summary
GlyTouCan ID
G40183QN
IUPAC Condensed
Neu5Ac(a2-8)Neu5Ac(a2-3)[Neu5Ac(a2-3)Gal(b1-3)GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs
GT1b
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
1580.53
GlyGen
ChEBI
PubChem Compound
PubChem Substance
Organisms
GlycoGene Database (GGDB)
Displaying 1 entry
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA5 CMP-Neu5Ac
G40183QN
Cer
G18625KA
Cer
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST8SIA5 CMP-Neu5Ac
G46677TE
Cer
G40183QN
Cer
ST8SIA6 CMP-Neu5Ac
G46677TE
Cer
G40183QN
Cer
ST8SIA5 CMP-Neu5Ac
G40183QN
Cer
G18625KA
Cer
ST8SIA6 CMP-Neu5Ac
G40183QN
Cer
G18625KA
Cer
ST8SIA1 CMP-Neu5Ac
G40183QN
Cer
G18625KA
Cer
Displaying all 3 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST8SIA3 CMP-Neu5Ac
G40183QN
Cer
ST8SIA2 CMP-Neu5Ac
G40183QN
Cer
B4GALNT1 UDP-GalNAc
G40183QN
Cer
KEGG BRITE Database
KEGG ID
Enzyme
References
Reactions
Displaying all 3 entries
KEGG Reaction Enzyme Acceptor Product
R05949
R05950
R05951
GlycoEpitope
Epitope ID
EP0067
Sequence Descriptors
GlycoCT
RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
7b:b-dgal-HEX-1:5
8s:n-acetyl
9b:b-dgal-HEX-1:5
10b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
11s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n
6:2o(4+1)7d
7:7d(2+1)8n
8:7o(3+1)9d
9:9o(3+2)10d
10:10d(5+1)11n
WURCS
WURCS=2.0/4,7,6/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-3-4-2-3/a4-b1_b3-c2_b4-e1_c8-d2_e3-f1_f3-g2
Literature
Displaying entries 1 - 10 of 26 in total
PubMed ID Title First Author Publication Date Source
17855742 Sulfatide binding properties of murine and human antiganglioside antibodies Townson K 2007 Aug 17
  • GlyGen
  • GlycoEpitope
16120058 Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins Teintenier-Lelièvre M 2005 Dec 06
  • PubChem
15967512 Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire Boffey J 2005 Aug
  • GlyGen
  • GlycoEpitope
15464996 Gangliosides of organ-confined versus metastatic androgen-receptor-negative prostate cancer Ravindranath MH 2004 Nov 05
  • GlyGen
  • GlycoEpitope
15223242 Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes Boffey J 2004 Jul
  • GlyGen
  • GlycoEpitope
14960498 Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera Willison HJ 2003 Nov 07
  • GlyGen
  • GlycoEpitope
12390975 Localization of major gangliosides in the PNS: implications for immune neuropathies Gong Y 2002 Nov
  • GlyGen
  • GlycoEpitope
11878808 Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides Schnaar RL 2002 Mar 15
  • GlyGen
  • GlycoEpitope
11980897 Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans Takashima S 2002 Jul 05
  • PubChem
11279053 Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition Vinson M 2001 Jun 08
  • GlyGen
  • GlycoEpitope

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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