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glucosaminyl (N-acetyl) transferase 1, core 2

Summary

Gene Symbol

Gcnt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14537

KEGG Gene ID

mmu:14537

PubChem

14537

Alliance of Genome Resources

MGI:95676

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Nucleotide-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q09324	Core 2 beta-1,6-N-acetylglucosaminyltransferase Core 2-branching enzyme Core2-GlcNAc-transferase Leukocyte type core 2 beta-1,6-N-acetylglucosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
glycoprotein biosynthetic process	ISS
glycoprotein biosynthetic process	ISO
O-glycan processing, core 2	ISS
O-glycan processing, core 2	ISO
O-glycan processing, core 2	IMP	9881978

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

O-glycan processing [inference]

O-glycan processing, core 2

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

cell adhesion molecule production

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

kidney morphogenesis

tissue morphogenesis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
extracellular space	ISO
extracellular space	IEA
trans-Golgi network	ISO
trans-Golgi network	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleotide binding	IEA
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	ISO
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	IDA	12954635 22056345
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta-1,3-galactosyl-o-glycosyl-glycoprotein beta-1,6-n-acetylglucosaminyltransferase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
transferase activity

KEGG BRITE Database

Orthology

K00727

Name

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102]

References

1329093

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05912	2.4.1.102	G00031MO	G00033MO
R05910	2.4.1.102 2.4.1.148	G57321FI	G00041MO

Rhea

RHEA:56212

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

RHEA:56216

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.102

PMID

Ortholog

Displaying entries **31 - 40** of 84 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	100490337	Xenbase:XB-GENE-996858
Caenorhabditis elegans	100492495	WB:WBGene00001643
Anolis carolinensis	100565751		ANOCA02327
Nomascus leucogenys	100590764		NOMLE17173
Loxodonta africana	100658096		LOXAF16932
Cavia porcellus	100730200		CAVPO10677
Cricetulus griseus	100767124		CRIGR21418
Sarcophilus harrisii	100921847		SARHA03138
Otolemur garnettii	100944573		OTOGA17756
Pan paniscus	100990909		PANPA39674