GlyCosmos Portal

Submissions

G00031MO

Summary

GlyTouCan ID: G00031MO
IUPAC Condensed: Gal(b1-3)GalNAc(a1-
Motifs: O-Glycan core 1 T antigen TF antigen
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 383.14

External Links

GlyConnect structure

1947

GlyGen

G00031MO

ChEBI

61820

PubChem Compound

5288347

PubChem Substance

252294787

CarbBank

3D Structures

GLYCAM: DGalpb1-3DGalpNAca1-OH

GlycoShape

G00031MO

Displaying 1 entry
Archetype	α	β
G00032MO	G00031MO	G01534TU

Organisms

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Organisms	Evidence
Gadus	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Rattus	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus

Gadus chalcogrammus (walleye pollock)

Pollachius [inference]

Pollachius pollachius (pollack)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig) [inference]

Sus scrofa domesticus (domestic pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Shigella [inference]

Shigella dysenteriae

FCB group [inference]

Bacteroidota/Chlorobiota group [inference]

Bacteroidota [inference]

Bacteroidia [inference]

Bacteroidales [inference]

Bacteroidaceae [inference]

Bacteroides [inference]

Bacteroides ovatus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC2	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10742600
ST3GAL4	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST3GAL3	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC1	CMP-Neu5Ac	G00031MO	O-glycan Synthesis	G56682BC	O-glycan Synthesis

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G00031MO	free	12235148
ST6GALNAC4	CMP-Neu5Ac	G00031MO	benzyl	11062056
ST6GALNAC3	CMP-Neu5Ac	G00031MO	Ser/Thr	10536037
ST3GAL3	CMP-Neu5Ac	G00031MO	Antifreeze glycoprotein	8288606
ST3GAL6	CMP-Neu5Ac	G00031MO	free	10206952

KEGG BRITE Database

KEGG ID

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO
R12704	2.4.3.3	G00031MO	G28694FA
R05912	2.4.1.102	G00031MO	G00033MO
R05913	2.4.3.4	G00031MO	G65562ZE

Core Protein

Displaying entries **1 - 10** of 50 in total

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UniProt ID	Protein Name	Reference	Source
D9N008	Epiglycanin	1125949 115878 571355	GlyConnect
O02197	Circulating cathodic antigen	7925469	GlyConnect
P00743	Coagulation factor X	6767721	GlyConnect
P01190	Pro-opiomelanocortin	7507111	GlyConnect
P01215	Glycoprotein hormones alpha chain	1967025 3335536	GlyGen
P01375	Tumor necrosis factor	8631363	GlyGen GlyConnect
P01588	Erythropoietin	22678432 32578997 8477709	GlyGen GlyConnect
P01824	Immunoglobulin heavy variable 4-39	6619128	GlyGen GlyConnect
P01860	Immunoglobulin heavy constant gamma 3	25759508	GlyGen GlyConnect GlyConnect GlyConnect
P01876	Immunoglobulin heavy constant alpha 1	1280920 20030399 2628063 4373463 7215351 9442070	GlyGen GlyConnect

GlycoEpitope

Epitope ID: EP0020

Pathway

Displaying **all 8** entries
Pathway Name	Organism
E.coli O107	Escherichia coli
E.coli O117	Escherichia coli
E.coli O185	Escherichia coli
E.coli O5ab	Escherichia coli
E.coli O5ac	Escherichia coli
E.coli O70	Escherichia coli
E.coli O71	Escherichia coli
E.coli O83	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(3+1)3d

WURCS

WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5]/1-2/a3-b1

Literature

Displaying entries **1 - 10** of **216** in total

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PubMed ID	Title	First Author	Publication Date	Source
33806155	Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells	Bagdonaite I	2021 Mar 25	GlyGen PubChem
34191522	The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's Disease	Wilkinson H	2021 Aug 6	GlyGen
33871970	Structural and Functional Characterization of SARS-CoV-2 RBD Domains Produced in Mammalian Cells	Gstottner C	2021 Apr 19	GlyGen PubChem
32973204	Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila	Trastoy B	2020 Sep 24	PubChem
32841605	Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor	Zhao P	2020 Oct 07	GlyGen PubChem
33030205	Structural evidence for a proline-specific glycopeptide recognition domain in an O-glycopeptidase	Noach I	2020 Oct 07	PubChem
32578997	Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin	Lippold S	2020 Jul 21	GlyGen PubChem
32310329	Comprehensive N- and O-glycosylation mapping of human coagulation factor V	Ma C	2020 Aug	GlyGen PubChem
31118252	GII.13/21 noroviruses recognize glycans with a terminal beta-galactose via an unconventional glycan binding site	Cong X	2019 May 22	PubChem
29507247	Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection	Kalas V	2018 Mar 05	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
The binding of simian virus 40 large T antigen to the polyphosphate backbone of nucleic acids.	Montenarh M Henning R	Biochim Biophys Acta	1982 Jun 30	6896661
Purification and characterization of the cytoplasmic casein kinase I from rat liver.	Pierre M Loeb JE	Biochim Biophys Acta	1982 Jan 18	6948579
Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity.	Clark R Lane DP Tjian R	J Biol Chem	1981 Nov 25	6170639
Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell.	Hanahan D Lane D Lipsich L Wigler M Botchan M	Cell	1980 Aug	6250708
A stretch of "late" SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes.	Varshavsky AJ Sundin O Bohn M	Cell	1979 Feb	222461

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements