Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
Guidelines
MIRAGE
Erythropoietin

Summary
UniProt ID
P01588
Gene Symbol
  • EPO
Gene ID
2056
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P01588
PubChem
P01588
Re-Glyco
P01588
Annotation
Keyword
  • 3D-structure
  • Congenital erythrocytosis
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Erythrocyte maturation
  • Glycoprotein
  • Hormone
  • Pharmaceutical
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 4 entries
GO Term
extracellular region
extracellular space
cell body
cell surface
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGVHECPAWLWLLLSLLSLPLGLPVLGAPPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTGEACRTGDR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
51 N-linked (GlcNAc...) asparagine
65 N-linked (GlcNAc...) asparagine
110 N-linked (GlcNAc...) asparagine
153 O-linked (GalNAc...) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Homo sapiens
Erythropoietin activates Phospholipase C gamma (PLCG) Homo sapiens
Erythropoietin activates RAS Homo sapiens
Erythropoietin activates STAT5 Homo sapiens
Regulation of gene expression by Hypoxia-inducible Factor Homo sapiens
Signaling by Erythropoietin Homo sapiens
Disease
Displaying entries 1 - 10 of 19 in total
DO ID Disease Name Source
DOID:0050852 limb ischemia
DOID:0080290 familial erythrocytosis 5
DOID:10652 Alzheimer's disease
DOID:11713 diabetic angiopathy
DOID:1184 nephrotic syndrome
DOID:1289 neurodegenerative disease
DOID:13268 porphyria
DOID:14330 Parkinson's disease
DOID:1686 glaucoma
DOID:224 transient cerebral ischemia
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.2.1

Last updated: April 7, 2025