Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
Guidelines
MIRAGE
Erythropoietin

Summary
UniProt ID
P01588
Gene Symbol
  • EPO
Gene ID
2056
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P01588
PubChem
P01588
Re-Glyco
P01588
Annotation
Keyword
  • 3D-structure
  • Congenital erythrocytosis
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Erythrocyte maturation
  • Glycoprotein
  • Hormone
  • Pharmaceutical
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 4 entries
GO Term
cell body
cell surface
extracellular region
extracellular space
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGVHECPAWLWLLLSLLSLPLGLPVLGAPPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTGEACRTGDR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
51 N-linked (GlcNAc...) asparagine
65 N-linked (GlcNAc...) asparagine
110 N-linked (GlcNAc...) asparagine
153 O-linked (GalNAc...) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Homo sapiens
Erythropoietin activates Phospholipase C gamma (PLCG) Homo sapiens
Erythropoietin activates RAS Homo sapiens
Erythropoietin activates STAT5 Homo sapiens
Regulation of gene expression by Hypoxia-inducible Factor Homo sapiens
Signaling by Erythropoietin Homo sapiens
Disease
Displaying entries 11 - 19 of 19 in total
DO ID Disease Name Source
DOID:3021 acute kidney failure
DOID:3070 high grade glioma
DOID:3525 middle cerebral artery infarction
DOID:3891 placental insufficiency
DOID:5844 myocardial infarction
DOID:6000 congestive heart failure
DOID:6432 pulmonary hypertension
DOID:8947 diabetic retinopathy
DOID:9743 diabetic neuropathy
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.2.1

Last updated: April 7, 2025