Tumor necrosis factor

Summary
UniProt ID
P01375
Gene Symbol
TNF TNFA TNFSF2
Gene ID
7124
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P01375
PubChem
P01375
The Human Metabolome Database
HMDBP02070
Re-Glyco
P01375
Annotation
Keyword
3D-structure Cell membrane Cytokine Direct protein sequencing Disulfide bond Glycoprotein Myristate Phosphoprotein Proteomics identification Reference proteome Secreted Signal-anchor Transmembrane helix
Gene Ontology (GO)
GO Hierarchy
Sequence
MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
80
  • O-linked (GalNAc...) serine; in soluble form
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying entries 1 - 10 of 83 in total
DO ID Disease Name Source
DOID:9744 type 1 diabetes mellitus
DOID:8725 vascular dementia
DOID:9538 multiple myeloma
DOID:409 liver disease
DOID:14453 farmer's lung
DOID:3770 pulmonary fibrosis
DOID:10325 silicosis
DOID:0070508 metabolic dysfunction and alcohol associated liver disease
DOID:0050848 obstructive sleep apnea
DOID:12449 aplastic anemia

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026