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gap junction protein, beta 6

Summary

Gene Symbol

Gjb6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14623

KEGG Gene ID

PubChem

14623

Alliance of Genome Resources

MGI:107588

Annotation

Keyword

Cell membrane
Gap junction
Hearing
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P70689	Connexin-30
Q3URC5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
cell communication	IEA
cell-cell signaling	IBA
sensory perception of sound	IMP
negative regulation of cell population proliferation	ISO
cell communication by electrical coupling	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication

intercellular transport [inference]

gap junction-mediated intercellular transport

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

gap junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

gap junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

gap junction assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

ear morphogenesis

sensory organ morphogenesis [inference]

ear morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

ear morphogenesis

anatomical structure development [inference]

inner ear development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to abiotic stimulus [inference]

response to electrical stimulus

response to chemical [inference]

response to lipid [inference]

response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose [inference]

cellular response to glucose stimulus

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

gap junction-mediated intercellular transport

transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
actin filament	ISO
actin filament	IEA
plasma membrane	IEA
gap junction	ISO
gap junction	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

connexin complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction [inference]

gap junction

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
gap junction channel activity	ISO
gap junction channel activity	IBA
gap junction channel activity	IEA
protein binding	IPI
microtubule binding	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

passive transmembrane transporter activity [inference]

channel activity [inference]

wide pore channel activity [inference]

gap junction channel activity

gap junction channel activity involved in cell communication by electrical coupling

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

tubulin binding [inference]

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:14693	Clouston syndrome	Alliance of Genome Resources
DOID:0110475	autosomal recessive nonsyndromic deafness 1A	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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