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solute carrier family 5 member 8

Summary

Gene Symbol

SLC5A8

Organism

Homo sapiens (human)

External Links

NCBI Gene

160728

KEGG Gene ID

PubChem

160728

Alliance of Genome Resources

HGNC:19119

Annotation

Keyword

3D-structure
Apoptosis
Cell membrane
Glycoprotein
Proteomics identification
Reference proteome
Sodium transport
Symport
Transmembrane helix
Tumor suppressor

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8N695	Apical iodide transporter Electrogenic sodium monocarboxylate cotransporter Sodium iodide-related cotransporter Solute carrier family 5 member 8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
sodium ion transport	IBA
chloride transport	IDA
acetate transport	IDA
pyruvate transport	IDA
apoptotic process

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

alkaloid metabolic process [inference]

nicotinate metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

nicotinate metabolic process

pyridine-containing compound metabolic process [inference]

nicotinate metabolic process

cell death [inference]

programmed cell death [inference]

apoptotic process

transmembrane transport

nitrate transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

carboxylic acid transmembrane transport [inference]

lactate transmembrane transport

fatty acid transmembrane transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic anion transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

lipid transport [inference]

fatty acid transport [inference]

short-chain fatty acid transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

fatty acid transmembrane transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

inorganic anion transport [inference]

nitrate import [inference]

nitrate transmembrane transport

organic anion transport

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

lactate transport

lactate transmembrane transport

fatty acid transport [inference]

short-chain fatty acid transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

fatty acid transmembrane transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

nicotinate transport

carboxylic acid transmembrane transport [inference]

lactate transmembrane transport

fatty acid transmembrane transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

lactate transport

lactate transmembrane transport

fatty acid transport [inference]

short-chain fatty acid transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

fatty acid transmembrane transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

nicotinate transport

carboxylic acid transmembrane transport [inference]

lactate transmembrane transport

fatty acid transmembrane transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

organic hydroxy compound transport [inference]

lactate transport

lactate transmembrane transport

transmembrane transport

nitrate transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

carboxylic acid transmembrane transport [inference]

lactate transmembrane transport

fatty acid transmembrane transport [inference]

short-chain fatty acid transmembrane transport [inference]

propanoate transmembrane transport

nitrogen compound transport [inference]

nitrate import [inference]

nitrate transmembrane transport

nicotinate transport

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
GINS complex	IEA
plasma membrane	TAS
plasma membrane	IBA
membrane	IEA
apical plasma membrane	EXP

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

DNA replication preinitiation complex [inference]

GINS complex

nuclear protein-containing complex [inference]

DNA replication preinitiation complex [inference]

GINS complex

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
organic acid:sodium symporter activity	IBA
organic acid:sodium symporter activity	IEA
protein binding	IPI
monocarboxylic acid transmembrane transporter activity	TAS
lactate transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

iodide channel activity

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity

organic acid:sodium symporter activity

monocarboxylate:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity

organic acid:sodium symporter activity

monocarboxylate:sodium symporter activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

iodide channel activity

iodide transmembrane transporter activity [inference]

iodide channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

iodide channel activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity

organic acid:sodium symporter activity

monocarboxylate:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity

lactate transmembrane transporter activity

fatty acid transmembrane transporter activity [inference]

short-chain fatty acid transmembrane transporter activity

propionate transmembrane transporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity

nicotinate transmembrane transporter activity

lipid transmembrane transporter activity [inference]

fatty acid transmembrane transporter activity [inference]

short-chain fatty acid transmembrane transporter activity

propionate transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

solute carrier family 5 member 5

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sodium/glucose symporter superfamily
Sodium/solute symporter

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	216225	MGI:2384916
Drosophila melanogaster	43136	FB:FBgn0250757
Drosophila melanogaster	326229	FB:FBgn0052669
Danio rerio	556156	ZFIN:ZDB-GENE-061110-98
Xenopus laevis	403396	Xenbase:XB-GENE-865289