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MIRAGE
integrin beta 3
Summary
- Gene Symbol
-
- Itgb3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cell projection
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Integrin
- Magnesium
- Metal-binding
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O54890 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of endothelial cell proliferation | ||
| positive regulation of endothelial cell proliferation | ||
| positive regulation of cell-matrix adhesion | ||
| positive regulation of leukocyte migration | ||
| cell-substrate junction assembly |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleoplasm | ||
| nucleoplasm | ||
| plasma membrane | ||
| cell-cell junction |
| GO Term | Evidence Code | PMID |
|---|---|---|
| fibronectin binding | ||
| fibronectin binding | ||
| fibronectin binding | ||
| protease binding | ||
| protease binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Integrin beta
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell adhesion mediated by integrin |
| cell migration |
| cell-matrix adhesion |
| integrin binding |
| integrin-mediated signaling pathway |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060691 | platelet-type bleeding disorder 16 | |
| DOID:2219 | Glanzmann's thrombasthenia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3688 | FB:FBgn0004657 | ||
| 3689 | FB:FBgn0004657 | ||
| 3690 | Xenbase:XB-GENE-1009964 | HUMAN34529 | |
| 3693 | FB:FBgn0004657 | ||
| 3694 | FB:FBgn0004657 | ||
| 3695 | FB:FBgn0004657 | ||
| 16412 | FB:FBgn0004657 | ||
| 16414 | FB:FBgn0004657 | ||
| 16416 | Xenbase:XB-GENE-1009964 | ||
| 16419 | FB:FBgn0004657 |
