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myeloperoxidase

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17523

KEGG Gene ID

PubChem

17523

Alliance of Genome Resources

MGI:97137

Annotation

Keyword

Calcium
Disulfide bond
Glycoprotein
Heme
Hydrogen peroxide
Lysosome
Oxidation
Reference proteome
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q7TMS4
Q571G0
P11247

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **31 - 34** of 34 in total

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GO Term	Evidence Code	PMID
neutrophil extracellular trap formation	ISO
neutrophil extracellular trap formation	IEA
positive regulation of cholesterol import	IEA
response to gold nanoparticle	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell

myeloid leukocyte mediated immunity [inference]

neutrophil mediated immunity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell

respiratory burst involved in defense response

cellular process [inference]

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

neutrophil mediated cytotoxicity [inference]

neutrophil-mediated killing of symbiont cell

killing of cells of another organism [inference]

neutrophil-mediated killing of symbiont cell

metabolic process [inference]

catabolic process [inference]

hydrogen peroxide catabolic process

biosynthetic process [inference]

small molecule biosynthetic process [inference]

hypochlorous acid biosynthetic process

reactive oxygen species biosynthetic process [inference]

hypochlorous acid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

hypochlorous acid biosynthetic process

small molecule biosynthetic process [inference]

hypochlorous acid biosynthetic process

respiratory burst [inference]

respiratory burst involved in defense response

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species biosynthetic process [inference]

hypochlorous acid biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

nucleosome organization [inference]

nucleosome disassembly

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

protein-DNA complex disassembly [inference]

nucleosome disassembly

cellular component assembly [inference]

neutrophil extracellular trap formation

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

protein-DNA complex disassembly [inference]

nucleosome disassembly

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

protein-DNA complex organization [inference]

protein-DNA complex disassembly [inference]

nucleosome disassembly

nucleosome organization [inference]

nucleosome disassembly

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to fungus [inference]

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism [inference]

neutrophil-mediated killing of symbiont cell

response to stimulus [inference]

response to stress [inference]

defense response

response to oxidative stress

response to external stimulus [inference]

response to mechanical stimulus

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to fungus [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to fungus [inference]

response to abiotic stimulus [inference]

response to mechanical stimulus

response to nutrient levels [inference]

response to food

response to chemical [inference]

response to food

response to lipid [inference]

response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to transition metal nanoparticle [inference]

response to gold nanoparticle

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

regulation of cholesterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

regulation of cholesterol import [inference]

positive regulation of cholesterol import

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

regulation of cholesterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

regulation of cholesterol import [inference]

positive regulation of cholesterol import

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol import

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space
nucleus	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule

azurophil granule

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

primary lysosome [inference]

azurophil granule

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule

azurophil granule

membraneless organelle [inference]

extracellular membraneless organelle [inference]

neutrophil extracellular trap

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

primary lysosome [inference]

azurophil granule

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

secretory granule

azurophil granule

extracellular organelle [inference]

extracellular membraneless organelle [inference]

neutrophil extracellular trap

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
peroxidase activity	ISS
peroxidase activity	ISO
peroxidase activity	IDA
peroxidase activity	IMP
peroxidase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on peroxide as acceptor [inference]

peroxidase activity

binding [inference]

chromatin binding [inference]

nucleosome binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

nucleosome binding

tetrapyrrole binding [inference]

heme binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

antioxidant activity [inference]

peroxidase activity

protein-containing complex destabilizing activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peroxidase

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cellular oxidant detoxification
heme binding
metal ion binding
oxidoreductase activity
response to oxidative stress

Displaying **all 3** entries
InterPro
Haem peroxidase domain superfamily, animal type
Haem peroxidase superfamily
Haem peroxidase, animal-type

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	181288	WB:WBGene00004257
Caenorhabditis elegans	191484	WB:WBGene00004256
Drosophila melanogaster	38326	FB:FBgn0011828
Homo sapiens	4353	HGNC:7218