GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein kinase activity	IEA
protein tyrosine kinase activity	IEA
transmembrane receptor protein tyrosine kinase activity	IEA
insulin receptor activity	ISS
insulin receptor activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

insulin receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

insulin receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

insulin receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

insulin receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

insulin receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

insulin receptor activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein domain specific binding [inference]

insulin receptor substrate binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

hormone binding [inference]

peptide hormone binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

insulin receptor activity

protein-hormone receptor activity [inference]

insulin receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 6** entries
Location	References
cytoplasmic vesicle	PMID:24120884
cytoplasm	PMID:24120884
neuronal cell body	PMID:22123849 PMID:25035490 PMID:36284093
plasma membrane	PMID:24120884 PMID:36284093
neuron projection	PMID:36284093
axon	PMID:22123849 PMID:25035490

Rhea

RHEA:10596

ATP

H⁺ + ADP

Enzyme

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:14330	Parkinson's disease	Alliance of Genome Resources
DOID:9351	diabetes mellitus	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP008162
Gene Name: Protein DAF-2

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	16001	MGI:96433
Mus musculus	16337	MGI:96575
Mus musculus	23920	MGI:1346037
Rattus norvegicus	25718	RGD:2869
Rattus norvegicus	60663	RGD:67399
Drosophila melanogaster	42549	FB:FBgn0283499
Homo sapiens	3480	HGNC:5465
Homo sapiens	3645	HGNC:6093
Homo sapiens	3643	HGNC:6091

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements