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Chromobox protein homolog hpl-2

Summary

Gene Symbol

hpl-2

Organism

Caenorhabditis elegans

External Links

NCBI Gene

176506

PubChem

176506

Alliance of Genome Resources

WB:WBGene00001996

Gene Ontology (GO)

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	PMID
nematode larval development	IGI	16905130
chromatin organization	IEA
phospholipid metabolic process	IMP	22185090
germ cell development	IMP	16905130
germ cell development	IGI	16905130

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular lipid metabolic process [inference]

phospholipid metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular process [inference]

cell cycle process [inference]

chromosome attachment to the nuclear envelope

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular lipid metabolic process [inference]

phospholipid metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular developmental process [inference]

cell fate specification [inference]

vulval cell fate specification

cell development [inference]

germ cell development

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization

chromatin remodeling [inference]

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

heterochromatin organization [inference]

heterochromatin formation

reproductive process

developmental process involved in reproduction [inference]

germ cell development

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

reproductive structure development [inference]

gonad development

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

olfactory learning

multicellular organism development [inference]

larval development [inference]

nematode larval development

dauer larval development

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

olfactory learning

chemosensory behavior [inference]

olfactory behavior [inference]

olfactory learning

determination of adult lifespan

post-embryonic development [inference]

larval development [inference]

nematode larval development

dauer larval development

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

reproductive structure development [inference]

gonad development

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

sensory organ morphogenesis [inference]

nematode male tail mating organ morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

anatomical structure development [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

dauer larval development

cell development [inference]

germ cell development

animal organ development [inference]

gonad development

reproductive structure development [inference]

gonad development

cellular developmental process [inference]

cell fate specification [inference]

vulval cell fate specification

cell development [inference]

germ cell development

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

localization [inference]

organelle localization [inference]

chromosome localization [inference]

chromosome attachment to the nuclear envelope

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

positive regulation of gene expression

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

positive regulation of gene expression

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

positive regulation of gene expression

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

regulation of growth [inference]

regulation of growth rate [inference]

positive regulation of growth rate

positive regulation of growth [inference]

positive regulation of growth rate

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of growth [inference]

positive regulation of growth rate

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of developmental process [inference]

negative regulation of post-embryonic development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

negative regulation of multicellular organismal process [inference]

negative regulation of post-embryonic development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

regulation of developmental process [inference]

regulation of vulval development [inference]

negative regulation of vulval development

regulation of cell differentiation

negative regulation of developmental process [inference]

negative regulation of post-embryonic development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

regulation of multicellular organismal development [inference]

regulation of post-embryonic development [inference]

negative regulation of post-embryonic development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

regulation of nematode larval development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

positive regulation of gene expression

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cell differentiation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of post-embryonic development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

regulation of multicellular organismal development [inference]

regulation of post-embryonic development [inference]

negative regulation of post-embryonic development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

regulation of nematode larval development [inference]

negative regulation of nematode larval development [inference]

negative regulation of vulval development

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	IDA	16905130
nucleus	IEA
nuclear inner membrane
chromosome	IEA
nuclear periphery	IDA	21116703

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

nuclear inner membrane

nuclear membrane [inference]

nuclear inner membrane

nuclear periphery

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
chromatin binding	IDA	23993094 25467431 29760282
protein binding	IPI	22083954 29760282
methylated histone binding	IPI	23028351
methylated histone binding	IEA
H3K27me3 modified histone binding	IPI	23028351