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LM-GlycoRepo

Repository for lectin-assisted multimodality data

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Other Information

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Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

Cathepsin L-like

Summary

Gene Symbol

cpl-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

180111

KEGG Gene ID

PubChem

180111

Alliance of Genome Resources

WB:WBGene00000776

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
Disulfide bond
Endosome
Glycoprotein
Lysosome
Reference proteome
Secreted
Signal
Thiol protease
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
O45734

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
proteolysis	IEA
apoptotic process	IEA
immune response	IBA
protein catabolic process	IBA
apoptotic cell clearance	IMP

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

protein metabolic process [inference]

primary metabolic process [inference]

protein metabolic process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

lipid droplet organization [inference]

lipid droplet disassembly

organelle disassembly [inference]

lipid droplet disassembly

cellular component disassembly [inference]

organelle disassembly [inference]

lipid droplet disassembly

response to stimulus [inference]

immune response

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

import into cell [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cellular component organization [inference]

positive regulation of vitellogenesis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of vitellogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of protein maturation [inference]

regulation of protein processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of protein maturation [inference]

regulation of protein processing

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptosis involved in tissue homeostasis

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cellular component organization [inference]

positive regulation of vitellogenesis

regulation of cellular component organization [inference]

positive regulation of cellular component organization [inference]

positive regulation of vitellogenesis

regulation of vitellogenesis [inference]

positive regulation of vitellogenesis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vitellogenesis

regulation of vitellogenesis [inference]

positive regulation of vitellogenesis

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
extracellular region	IDA
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space
cytoplasm	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen

yolk granule

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endolysosome

endocytic vesicle [inference]

phagocytic vesicle

phagolysosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

secondary lysosome

phagolysosome

endolysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endolysosome

endocytic vesicle [inference]

phagocytic vesicle

phagolysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

secondary lysosome

phagolysosome

endolysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endolysosome

endocytic vesicle [inference]

phagocytic vesicle

phagolysosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cysteine-type endopeptidase activity	ISS
cysteine-type endopeptidase activity	IBA
cysteine-type endopeptidase activity	IEA
protein binding	IPI
cysteine-type peptidase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity

cysteine-type peptidase activity

cysteine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

cysteine-type endopeptidase activity

cysteine-type peptidase activity

cysteine-type endopeptidase activity

binding [inference]

protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

peptidase activator activity [inference]

peptidase activator activity involved in apoptotic process [inference]

cysteine-type endopeptidase activator activity involved in apoptotic process

cysteine-type endopeptidase regulator activity involved in apoptotic process [inference]

cysteine-type endopeptidase activator activity involved in apoptotic process

peptidase regulator activity [inference]

peptidase activator activity [inference]

peptidase activator activity involved in apoptotic process [inference]

cysteine-type endopeptidase activator activity involved in apoptotic process

molecular function activator activity [inference]

enzyme activator activity [inference]

peptidase activator activity [inference]

peptidase activator activity involved in apoptotic process [inference]

cysteine-type endopeptidase activator activity involved in apoptotic process

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 5** entries
Location	References
annuli extracellular matrix	PMID:11707440
lysosome	PMID:24829385
collagen and cuticulin-based cuticle extracellular matrix	PMID:11707440
phagolysosome	PMID:24829385
endolysosome	PMID:22768338

Ortholog

Displaying entries **1 - 10** of 14 in total

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Species	Gene ID	Alliance of Genome Resources
Mus musculus	56092	MGI:1860262
Mus musculus	214639	MGI:1922258
Mus musculus	56835	MGI:1861723
Mus musculus	13039	MGI:88564
Mus musculus	56094	MGI:1860275
Mus musculus	64139	MGI:1927229
Mus musculus	26898	MGI:1349426
Rattus norvegicus	286916	RGD:708447
Rattus norvegicus	29174	RGD:69241
Rattus norvegicus	246147	RGD:631421

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026