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MIRAGE
dipeptidyl peptidase like 6
Summary
- Gene Symbol
-
- DPP6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Aminopeptidase
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Intellectual disability
- Neurodegeneration
- Proteomics identification
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8IYG9 |
|
| E9PF59 |
|
| A7E2E4 |
|
| E9PDL2 |
|
| P42658 |
|
| B7Z299 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| protein localization to plasma membrane | ||
| regulation of potassium ion transmembrane transport | ||
| regulation of potassium ion transmembrane transport | ||
| regulation of potassium ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| voltage-gated potassium channel complex | ||
| voltage-gated potassium channel complex | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| serine-type peptidase activity | ||
| dipeptidyl-peptidase activity | ||
| potassium channel regulator activity | ||
| potassium channel regulator activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- peptidase
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| dipeptidyl-peptidase activity |
| proteolysis |
| serine-type peptidase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Dipeptidylpeptidase IV, N-terminal domain |
| Peptidase S9, prolyl oligopeptidase, catalytic domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070063 | autosomal dominant intellectual developmental disorder 33 | |
| DOID:12377 | spinal muscular atrophy | |
| DOID:332 | amyotrophic lateral sclerosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115573062 | SPAAU38564 | ||
| 115609034 | STRHB15479 | ||
| 116439435 | CORMO09104 | ||
| 116822048 | CHEAB08334 | ||
| 117018147 | RHIFE12099 | ||
| 118900821 | BALMU11782 | ||
| 122213038 | PANLE21772 |
