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MIRAGE
NPC intracellular cholesterol transporter 1 homolog 1
Summary
- Gene Symbol
-
- ncr-1
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Developmental protein
- Disulfide bond
- Glycoprotein
- Lipid transport
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q19127 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| sterol transport |
|
|
| intestinal cholesterol absorption |
|
|
| cholesterol transport |
|
|
| positive regulation of growth rate |
|
|
| dauer larval development |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| lysosome |
|
|
| late endosome |
|
|
| plasma membrane |
|
|
| membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| molecular_function |
|
|
| cholesterol binding |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- transporter
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cholesterol binding |
| intestinal cholesterol absorption |
| lipid transport |
| sterol transport |
| InterPro |
|---|
| Niemann-Pick C1, N-terminal |
| Protein patched/dispatched |
| Sterol-sensing domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14504 | Niemann-Pick disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 18145 | MGI:1097712 | |
| 432367 | RGD:1303135 | |
| 33072 | FB:FBgn0261675 | |
| 29881 | HGNC:7898 | |
| 4864 | HGNC:7897 | |
| 856101 | SGD:S000005927 |
