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pyruvate dehydrogenase kinase, isoenzyme 2

Summary

Gene Symbol

Pdk2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18604

KEGG Gene ID

PubChem

18604

Alliance of Genome Resources

MGI:1343087

Annotation

Keyword

ATP-binding
Kinase
Mitochondrion
Phosphoprotein
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JK42	Pyruvate dehydrogenase kinase isoform 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
regulation of gluconeogenesis	IMP
protein phosphorylation	ISO
regulation of pH	IMP
insulin receptor signaling pathway	IMP
regulation of pyruvate decarboxylation to acetyl-CoA	IMP

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

peptidyl-serine phosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

peptidyl-serine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

peptidyl-serine phosphorylation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species

cellular response to chemical stimulus [inference]

cellular response to nutrient

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

regulation of pH

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species

response to nutrient levels [inference]

response to nutrient [inference]

cellular response to nutrient

cellular response to nutrient levels [inference]

cellular response to nutrient

response to chemical [inference]

response to nutrient [inference]

cellular response to nutrient

cellular response to chemical stimulus [inference]

cellular response to nutrient

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to nutrient

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species

cellular response to chemical stimulus [inference]

cellular response to nutrient

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species

biological regulation [inference]

regulation of pH

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

intracellular signal transduction [inference]

signal transduction by p53 class mediator [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway by p53 class mediator

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis

regulation of acyl-CoA biosynthetic process [inference]

regulation of pyruvate decarboxylation to acetyl-CoA

regulation of ketone metabolic process

regulation of fatty acid metabolic process [inference]

regulation of acyl-CoA biosynthetic process [inference]

regulation of pyruvate decarboxylation to acetyl-CoA

regulation of sulfur metabolic process [inference]

regulation of acyl-CoA biosynthetic process [inference]

regulation of pyruvate decarboxylation to acetyl-CoA

regulation of phosphorus metabolic process [inference]

regulation of acyl-CoA biosynthetic process [inference]

regulation of pyruvate decarboxylation to acetyl-CoA

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process

regulation of gluconeogenesis

regulation of fatty acid metabolic process [inference]

regulation of acyl-CoA biosynthetic process [inference]

regulation of pyruvate decarboxylation to acetyl-CoA

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process

regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of acyl-CoA biosynthetic process [inference]

regulation of pyruvate decarboxylation to acetyl-CoA

regulation of nucleobase-containing compound metabolic process [inference]

regulation of acyl-CoA biosynthetic process [inference]

regulation of pyruvate decarboxylation to acetyl-CoA

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
mitochondrion	ISO
mitochondrion	IDA
mitochondrion	IBA
mitochondrion	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

oxidoreductase complex [inference]

alpha-ketoacid dehydrogenase complex [inference]

pyruvate dehydrogenase complex

transferase complex [inference]

acetyltransferase complex [inference]

pyruvate dehydrogenase complex

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
protein kinase activity	IEA
protein serine/threonine kinase activity	ISO
pyruvate dehydrogenase (acetyl-transferring) kinase activity	ISO
pyruvate dehydrogenase (acetyl-transferring) kinase activity	IMP
pyruvate dehydrogenase (acetyl-transferring) kinase activity	IBA