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exon junction complex subunit

Summary

Gene Symbol

Casc3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

192160

PubChem

192160

Alliance of Genome Resources

MGI:2179723

Annotation

Keyword

ADP-ribosylation
Cell projection
Coiled coil
Cytoplasm
Nonsense-mediated mRNA decay
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Spliceosome
Stress response
Translation regulation
Ubl conjugation
mRNA transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K3W3	Cancer susceptibility candidate gene 3 protein homolog Metastatic lymph node gene 51 protein homolog Protein barentsz

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
mRNA splicing, via spliceosome	ISS
mRNA splicing, via spliceosome	ISO
mRNA splicing, via spliceosome	IEA
mRNA processing	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA processing

mRNA splicing, via spliceosome

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

mRNA metabolic process [inference]

mRNA processing

mRNA splicing, via spliceosome

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

RNA processing [inference]

mRNA processing

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

localization [inference]

macromolecule localization [inference]

RNA localization [inference]

intracellular mRNA localization

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of mRNA catabolic process [inference]

regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of catabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of mRNA catabolic process [inference]

regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of protein metabolic process [inference]

regulation of translation

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

regulation of protein metabolic process [inference]

regulation of translation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IDA
nucleus	IEA
nucleoplasm	IEA
spliceosomal complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

spliceosomal complex

U2-type spliceosomal complex [inference]

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome [inference]

U2-type catalytic step 2 spliceosome

post-spliceosomal complex

exon-exon junction complex

catalytic complex [inference]

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome [inference]

U2-type catalytic step 2 spliceosome

ribonucleoprotein complex

spliceosomal complex

U2-type spliceosomal complex [inference]

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome [inference]

U2-type catalytic step 2 spliceosome

post-spliceosomal complex

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

nuclear membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

cytoplasmic stress granule

nuclear ribonucleoprotein granule [inference]

nuclear speck

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

cytoplasmic stress granule

nuclear ribonucleoprotein granule [inference]

nuclear speck

perinuclear region of cytoplasm

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

cytoplasmic stress granule

nuclear ribonucleoprotein granule [inference]

nuclear speck

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
RNA binding	IEA
mRNA binding	IEA
protein binding	IPI
enzyme binding	ISO
enzyme binding	IEA

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

mRNA binding

protein binding

enzyme binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CASC3

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
mRNA processing
mRNA transport
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Displaying 1 entry
InterPro
Btz domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements