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nectin cell adhesion molecule 1

Summary

Gene Symbol

Nectin1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

192183

KEGG Gene ID

PubChem

192183

Alliance of Genome Resources

RGD:620791

Annotation

Keyword

Cell adhesion
Cell junction
Cell membrane
Disulfide bond
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6J3U6	Herpes virus entry mediator C Nectin cell adhesion molecule 1 Poliovirus receptor-related protein 1
F1LNP8	Herpes virus entry mediator C Nectin cell adhesion molecule 1 Poliovirus receptor-related protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
lens morphogenesis in camera-type eye	ISO
desmosome organization	ISO
iron ion transport	ISO
homophilic cell-cell adhesion	ISO
homophilic cell-cell adhesion	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

cell-cell junction organization [inference]

desmosome organization

developmental process [inference]

anatomical structure morphogenesis [inference]

lens morphogenesis in camera-type eye

animal organ morphogenesis [inference]

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

camera-type eye morphogenesis

embryonic morphogenesis [inference]

cochlea morphogenesis

anatomical structure development [inference]

tissue development [inference]

biomineral tissue development [inference]

tooth mineralization [inference]

enamel mineralization

retina development in camera-type eye

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

symbiont entry into host [inference]

symbiont entry into host cell

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to cell junction

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport

biological regulation [inference]

regulation of biological process [inference]

regulation of biological process involved in symbiotic interaction [inference]

modulation by symbiont of entry into host [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

positive regulation of biological process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of viral life cycle [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization

regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA
adherens junction	ISO
adherens junction	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic active zone membrane

cell junction [inference]

synapse [inference]

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

anchoring junction [inference]

cell-cell junction [inference]

growth cone membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

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GO Term	Evidence Code	PMID
virus receptor activity	ISO
virus receptor activity	IBA
virus receptor activity	IEA
protein binding	IPI
carbohydrate binding	IDA

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

protein homodimerization activity

virion binding

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding

cell adhesion mediator activity

exogenous protein binding [inference]

virus receptor activity

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nectin-1

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
homophilic cell adhesion via plasma membrane adhesion molecules
protein localization to cell junction

Displaying **all 8** entries
InterPro
CD80-like, immunoglobulin C2-set
Immunoglobulin V-set domain
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Nectin-1, first immunoglobulin variable domain
Nectin-1, second immunoglobulin domain

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
dendrite	PMID:16801389
growth cone membrane	PMID:18181141
axon	PMID:16801389

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	58235	MGI:1926483
Homo sapiens	5818	HGNC:9706
Danio rerio	557665	ZFIN:ZDB-GENE-090224-2
Danio rerio	100136836	ZFIN:ZDB-GENE-090224-1

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements