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Nectin-1

Summary

UniProt ID: F1LNP8
Gene Symbol: Nectin1 Pvrl1
Gene ID: 192183
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: F1LNP8
Re-Glyco: F1LNP8

Annotation

Keyword: Cell adhesion Cell junction Cell membrane Disulfide bond Glycoprotein Host cell receptor for virus entry Host-virus interaction Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
lens morphogenesis in camera-type eye	ISO	GO_REF
desmosome organization	ISO	GO_REF
iron ion transport	ISO	GO_REF
homophilic cell-cell adhesion	ISO	GO_REF
homophilic cell-cell adhesion	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

cell-cell junction organization [inference]

desmosome organization

developmental process [inference]

anatomical structure morphogenesis [inference]

lens morphogenesis in camera-type eye

animal organ morphogenesis [inference]

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

camera-type eye morphogenesis

embryonic morphogenesis [inference]

cochlea morphogenesis

anatomical structure development [inference]

tissue development [inference]

biomineral tissue development [inference]

tooth mineralization [inference]

enamel mineralization

retina development in camera-type eye

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

symbiont entry into host [inference]

symbiont entry into host cell

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to cell junction

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport

biological regulation [inference]

regulation of biological process [inference]

regulation of biological process involved in symbiotic interaction [inference]

modulation by symbiont of entry into host [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

positive regulation of biological process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

positive regulation by symbiont of entry into host [inference]

positive regulation of viral entry into host cell

regulation of viral process [inference]

positive regulation of viral process [inference]

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of viral life cycle [inference]

regulation of viral entry into host cell [inference]

positive regulation of viral entry into host cell

positive regulation of viral life cycle [inference]

positive regulation of viral entry into host cell

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization

regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

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GO Term	Evidence Code	Reference
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF
adherens junction	ISO	GO_REF
adherens junction	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic active zone membrane

cell junction [inference]

synapse [inference]

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

anchoring junction [inference]

cell-cell junction [inference]

growth cone membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
virus receptor activity	ISO	GO_REF
virus receptor activity	IBA	GO_REF
virus receptor activity	IEA	GO_REF GO_REF
carbohydrate binding	IDA	PMID
signaling receptor activity	ISO	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding

protein homodimerization activity

virion binding

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding

cell adhesion mediator activity

exogenous protein binding [inference]

virus receptor activity

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MARMGLAGAAGRWWGLALGLTAFFLPGTHTQVVQVNDSMYGFIGTDVILHCSFANPLPTVKITQVTWQKASNGSKQNMAIYNPTMGVSVLPPYEKRVEFLRPSFIDGTIRLSHLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRARKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHRQSLACIVNYHLDRFRESLTLNVQYEPEVTIEGFDGNWYLQRTDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFRGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPTPEHGRRAGQMPTAIIGGVAGSVLLVLIVVGGIIVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites