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Guidelines

MIRAGE

eukaryotic translation initiation factor 4 gamma 1

Summary

Gene Symbol

EIF4G1

Organism

Homo sapiens (human)

External Links

NCBI Gene

1981

KEGG Gene ID

PubChem

1981

Alliance of Genome Resources

HGNC:3296

Annotation

Keyword

3D-structure
Acetylation
Alternative initiation
Alternative splicing
Cytoplasm
Disease variant
Host-virus interaction
Initiation factor
Methylation
Neurodegeneration
Nucleus
Parkinson disease
Parkinsonism
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Translation regulation
Translational shunt

Proteins

Displaying **all 6** entries
UniProt	Protein Name
Q96I65
O95065
B2RU06
B4DSI9
B2RU10
Q04637	p220

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
behavioral fear response
cap-dependent translational initiation	TAS
translation	IMP
translation	IPI
translational initiation	NAS

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

translational initiation

cytoplasmic translational initiation [inference]

cap-dependent translational initiation

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translation

protein metabolic process [inference]

translation

primary metabolic process [inference]

protein metabolic process [inference]

translation

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cellular response to stimulus [inference]

cellular response to nutrient levels

multicellular organismal process [inference]

behavior [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

multicellular organismal-level homeostasis [inference]

energy homeostasis

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

response to nutrient levels [inference]

cellular response to nutrient levels

cellular response to stimulus [inference]

cellular response to nutrient levels

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery

regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to cell periphery

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of protein metabolic process

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of cell growth

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of catabolic process [inference]

negative regulation of autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of response to stimulus [inference]

regulation of response to stress [inference]

regulation of cellular response to stress

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of translational initiation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of translation in response to stress [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

regulation of translation in response to endoplasmic reticulum stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of catabolic process [inference]

negative regulation of autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of protein metabolic process

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy

regulation of autophagy [inference]

negative regulation of autophagy

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of translational initiation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of translation in response to stress [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

regulation of translation in response to endoplasmic reticulum stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of protein metabolic process

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of protein metabolic process [inference]

regulation of translation

regulation of translational initiation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of translation in response to stress [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

regulation of translation in response to endoplasmic reticulum stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of protein metabolic process

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation

regulation of translational initiation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of translation in response to stress [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

regulation of translation in response to endoplasmic reticulum stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of protein metabolic process

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

regulation of eukaryotic translation initiation factor 4F complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of protein metabolic process

positive regulation of translation [inference]

positive regulation of translation in response to stress [inference]

positive regulation of translation in response to endoplasmic reticulum stress

positive regulation of cell growth

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of catabolic process [inference]

negative regulation of autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated gene silencing by inhibition of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

miRNA-mediated gene silencing by inhibition of translation

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

regulation of eukaryotic translation initiation factor 4F complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of presynapse organization [inference]

regulation of presynapse assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of eukaryotic translation initiation factor 4F complex assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle process [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

positive regulation of cell cycle G1/S phase transition [inference]

positive regulation of G1/S transition of mitotic cell cycle

regulation of cellular response to stress

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
nucleus	IDA
nucleus	IMP
nucleus	IEA
cytoplasm	IDA
cytoplasm	IMP

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

RNA cap binding complex [inference]

eukaryotic translation initiation factor 4F complex

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribosome

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

ribosome

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

Displaying entries **16 - 17** of 17 in total

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GO Term	Evidence Code	PMID
translation initiation factor binding	TAS
molecular adaptor activity	TAS

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

mRNA binding

protein binding

translation initiation factor binding

eukaryotic initiation factor 4E binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular adaptor activity

translation factor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Eukaryotic translation initiation factor 4 gamma

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
InterPro
Armadillo-type fold
Initiation factor 4G
Initiation factor eIF-4 gamma, MA3
MIF4G-like, type 3
W2 domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060892	late onset Parkinson's disease	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	208643	MGI:2384784
Drosophila melanogaster	43839	FB:FBgn0023213
Saccharomyces cerevisiae S288C	852833	SGD:S000003017
Saccharomyces cerevisiae S288C	853071	SGD:S000003394

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

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Last updated: April 6, 2026