GlyCosmos Portal

Submissions

complement factor H-related 4

Summary

Gene Symbol

Cfhr4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

214403

PubChem

214403

Alliance of Genome Resources

MGI:3646434

Annotation

Keyword

Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Sushi

Proteins

Displaying **all 5** entries
UniProt	Protein Name
E9Q8B5
Q0KHD3
Q0KHD2
B2RUG5
E9Q8B6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteolysis	ISO
complement activation	ISO
complement activation	IBA
regulation of complement activation	ISO
regulation of complement activation, alternative pathway	ISO

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation

activation of immune response [inference]

complement activation

immune response [inference]

humoral immune response [inference]

complement activation

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

response to stimulus [inference]

immune response [inference]

humoral immune response [inference]

complement activation

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

regulation of immune effector process [inference]

regulation of complement activation

regulation of complement activation, alternative pathway

regulation of immune response [inference]

regulation of humoral immune response [inference]

regulation of complement activation

regulation of complement activation, alternative pathway

regulation of innate immune response [inference]

regulation of complement activation, alternative pathway

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of innate immune response [inference]

regulation of complement activation, alternative pathway

regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

regulation of complement activation, alternative pathway

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

regulation of immune response [inference]

regulation of humoral immune response [inference]

regulation of complement activation

regulation of complement activation, alternative pathway

regulation of innate immune response [inference]

regulation of complement activation, alternative pathway

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of innate immune response [inference]

regulation of complement activation, alternative pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IDA	17028856
extracellular space	IBA
symbiont cell surface	ISO
serine-type endopeptidase complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

peptidase complex [inference]

serine-type peptidase complex [inference]

serine-type endopeptidase complex

endopeptidase complex [inference]

serine-type endopeptidase complex

cellular anatomical entity [inference]

extracellular space

other organism part [inference]

symbiont cell surface

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
complement component C3b binding	IBA
complement component C3b binding	IPI	17028856
heparin binding	ISO
heparin binding	IDA	17028856
identical protein binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

opsonin binding [inference]

complement component C3b binding

complement binding [inference]

complement component C3b binding

identical protein binding

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

sulfur compound binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

complement factor H

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
complement activation
complement component C3b binding

Displaying **all 2** entries
InterPro
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

Ortholog

Displaying entries **1 - 10** of 37 in total

1

2

3

4

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	2165	ZFIN:ZDB-GENE-041114-123
Homo sapiens	3075	ZFIN:ZDB-GENE-050208-342	HUMAN53976
Danio rerio	3078	ZFIN:ZDB-GENE-041114-123
Danio rerio	10877	ZFIN:ZDB-GENE-050208-423
Danio rerio	12628	ZFIN:ZDB-GENE-050208-342
Danio rerio	50702	ZFIN:ZDB-GENE-050208-342
Danio rerio	81494	ZFIN:ZDB-GENE-041114-123
Rattus norvegicus	155012		RATNO06818
Rattus norvegicus	185381	RGD:620428
Danio rerio	214403	ZFIN:ZDB-GENE-050208-342