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Repository for lectin-assisted multimodality data
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MIRAGE
coagulation factor II, thrombin
Summary
- Gene Symbol
-
- F2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Calcium
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Gamma-carboxyglutamic acid
- Glycoprotein
- Kringle
- Pharmaceutical
- Proteomics identification
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Thrombophilia
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P00734 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
|
|
| proteolysis |
|
|
| proteolysis |
|
|
| proteolysis |
|
|
| acute-phase response |
|
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
positive regulation of transport [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lipopolysaccharide binding |
|
|
| endopeptidase activity |
|
|
| serine-type endopeptidase activity |
|
|
| serine-type endopeptidase activity |
|
|
| serine-type endopeptidase activity |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- coagulation factor II, thrombin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1727 | retinal vein occlusion | |
| DOID:3526 | cerebral infarction | |
| DOID:12205 | dengue disease | |
| DOID:10159 | osteonecrosis | |
| DOID:0060903 | thrombosis | |
| DOID:3393 | coronary artery disease | |
| DOID:10591 | pre-eclampsia | |
| DOID:13001 | carotid stenosis | |
| DOID:9477 | pulmonary embolism | |
| DOID:2048 | autoimmune hepatitis |
