Prothrombin
| GO Term | Evidence Code | Reference |
|---|---|---|
| proteolysis | ||
| proteolysis | ||
| proteolysis | ||
| proteolysis | ||
| acute-phase response |
|
|
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
| GO Term | Evidence Code | Reference |
|---|---|---|
| lipopolysaccharide binding | ||
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| signaling receptor binding |
| Pathway Name | Organism |
|---|---|
| Amplification and propagation of coagulation cascade | Homo sapiens |
| Cell surface interactions at the vascular wall | Homo sapiens |
| Defective F8 cleavage by thrombin | Homo sapiens |
| Defective factor XII causes hereditary angioedema | Homo sapiens |
| Dengue Virus-Host Interactions | Homo sapiens |
| Fibrin formation | Homo sapiens |
| G alpha (q) signalling events | Homo sapiens |
| Gamma-carboxylation of protein precursors | Homo sapiens |
| Initiation of coagulation cascade | Homo sapiens |
| Peptide ligand-binding receptors | Homo sapiens |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10159 | osteonecrosis | |
| DOID:9074 | systemic lupus erythematosus | |
| DOID:12134 | factor VIII deficiency | |
| DOID:10608 | celiac disease | |
| DOID:5844 | myocardial infarction | |
| DOID:2235 | prothrombin deficiency | |
| DOID:5614 | eye disease | |
| DOID:3393 | coronary artery disease | |
| DOID:2921 | glomerulonephritis | |
| DOID:10591 | pre-eclampsia |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: April 6, 2026