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MIRAGE
coagulation factor V

Summary
Gene Symbol
  • F5
Organism
Homo sapiens (human)
NCBI Gene
2153
KEGG Gene ID
PubChem
2153
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Calcium
  • Copper
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Sulfation
  • Thrombophilia
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
P12259
  • Activated protein C cofactor
  • Proaccelerin, labile factor
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
proteolysis
blood coagulation
blood coagulation
blood coagulation, extrinsic pathway
blood circulation
GO Hierarchy
Displaying entries 6 - 10 of 18 in total
GO Term Evidence Code PMID
endoplasmic reticulum lumen
plasma membrane
membrane
membrane
COPII-coated ER to Golgi transport vesicle
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
coagulation factor VIII
Functional Category
  • G: Carbohydrate transport and metabolism
  • P: Inorganic ion transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 2 entries
Gene Ontology
copper ion binding
oxidoreductase activity
Displaying all 7 entries
InterPro
Coagulation factor 5/8 C-terminal domain
Coagulation factor 5/8-like
Cupredoxin
Galactose-binding-like domain superfamily
Multicopper oxidase, C-terminal
Multicopper oxidase-like, N-terminal
Multicopper oxidases, conserved site
Disease
Disease Ontology
Displaying entries 1 - 10 of 17 in total
DO ID Disease Name Source
DOID:1612 breast cancer
DOID:0111902 thrombophilia due to activated protein C resistance
DOID:6432 pulmonary hypertension
DOID:3526 cerebral infarction
DOID:5082 liver cirrhosis
DOID:9477 pulmonary embolism
DOID:5844 myocardial infarction
DOID:999 hypereosinophilic syndrome
DOID:1727 retinal vein occlusion
DOID:10003 sensorineural hearing loss
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026