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toll-like receptor 4

Summary

Gene Symbol

Tlr4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21898

PubChem

21898

Alliance of Genome Resources

MGI:96824

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disease variant
Disulfide bond
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
L0CL36
Q9QUK6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of **172** in total

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GO Term	Evidence Code	PMID
microglial cell activation	ISO
positive regulation of cytokine production	IEA
activation of innate immune response	IMP
toll-like receptor signaling pathway	ISO
toll-like receptor signaling pathway	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

activation of immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response

innate immune response

leukocyte activation

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation

microglial cell activation

mast cell activation

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

leukocyte activation

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation

microglial cell activation

mast cell activation

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

glial cell activation [inference]

microglial cell activation

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

lipopolysaccharide-mediated signaling pathway

signal transduction involved in regulation of gene expression

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

ERK1 and ERK2 cascade

canonical NF-kappaB signal transduction

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

mononuclear cell differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

glial cell differentiation [inference]

microglia differentiation

neurogenesis

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

cell development [inference]

glial cell development [inference]

astrocyte development

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

leukocyte activation

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation

microglial cell activation

mast cell activation

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

glial cell activation [inference]

microglial cell activation

production of molecular mediator involved in inflammatory response [inference]

nitric oxide production involved in inflammatory response

system process [inference]

digestive system process [inference]

maintenance of gastrointestinal epithelium [inference]

intestinal epithelial structure maintenance

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium [inference]

intestinal epithelial structure maintenance

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

bone morphogenesis

cartilage morphogenesis [inference]

growth plate cartilage morphogenesis

tissue morphogenesis [inference]

cartilage morphogenesis [inference]

growth plate cartilage morphogenesis

anatomical structure development [inference]

cell development [inference]

glial cell development [inference]

astrocyte development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

mononuclear cell differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

glial cell differentiation [inference]

microglia differentiation

neurogenesis

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

cell development [inference]

glial cell development [inference]

astrocyte development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium [inference]

intestinal epithelial structure maintenance

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to bacterium

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to oxidative stress

response to wounding [inference]

wound healing [inference]

wound healing involved in inflammatory response

immune response

innate immune response

response to external stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of pain

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of pain

cellular response to mechanical stimulus

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to lipopolysaccharide

response to lipoteichoic acid [inference]

cellular response to lipoteichoic acid

cellular response to molecule of bacterial origin [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to lipopolysaccharide

response to lipoteichoic acid [inference]

cellular response to lipoteichoic acid

cellular response to molecule of bacterial origin [inference]

response to other organism [inference]

response to bacterium

defense response to bacterium

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of pain

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of pain

cellular response to mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

response to growth factor [inference]

response to platelet-derived growth factor [inference]

cellular response to platelet-derived growth factor stimulus

cellular response to growth factor stimulus [inference]

cellular response to platelet-derived growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to platelet-derived growth factor stimulus

response to chemical [inference]

response to lipid [inference]

response to lipopolysaccharide

response to fatty acid

cellular response to lipid [inference]

cellular response to lipopolysaccharide

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

response to peptide [inference]

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

response to nitrogen compound [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to lipoteichoic acid [inference]

cellular response to lipoteichoic acid

response to fatty acid

response to alcohol [inference]

response to ethanol

cellular response to oxygen-containing compound [inference]

response to amyloid-beta [inference]

cellular response to amyloid-beta

detection of stimulus

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of pain

detection of chemical stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of pain

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

regulation of macrophage activation [inference]

positive regulation of macrophage activation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of dendritic cell cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of leukocyte mediated immunity [inference]

regulation of dendritic cell cytokine production

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade [inference]

regulation of JNK cascade [inference]

positive regulation of JNK cascade

regulation of ERK1 and ERK2 cascade [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of platelet activation

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of response to cytokine stimulus [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of platelet activation

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cold-induced thermogenesis

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade [inference]

regulation of JNK cascade [inference]

positive regulation of JNK cascade

regulation of ERK1 and ERK2 cascade [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of inflammatory response

positive regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of response to cytokine stimulus [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of response to cytokine stimulus [inference]

positive regulation of response to cytokine stimulus [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

regulation of cellular response to macrophage colony-stimulating factor stimulus [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of inflammatory response

positive regulation of inflammatory response

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

regulation of cellular process [inference]

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

MyD88-dependent toll-like receptor signaling pathway

MyD88-independent toll-like receptor signaling pathway [inference]

TRIF-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

lipopolysaccharide-mediated signaling pathway

signal transduction involved in regulation of gene expression

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

ERK1 and ERK2 cascade

canonical NF-kappaB signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of intracellular signal transduction [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway

regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [inference]

positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade [inference]

regulation of JNK cascade [inference]

positive regulation of JNK cascade

regulation of ERK1 and ERK2 cascade [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of dendritic cell cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of type II interferon production [inference]

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-13 production [inference]

positive regulation of interleukin-13 production

regulation of interleukin-17 production [inference]

negative regulation of interleukin-17 production

regulation of interleukin-23 production [inference]

negative regulation of interleukin-23 production

regulation of interleukin-6 production [inference]

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of dendritic cell cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of MHC class II biosynthetic process [inference]

positive regulation of MHC class II biosynthetic process

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of dendritic cell cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of type II interferon production [inference]

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-13 production [inference]

positive regulation of interleukin-13 production

regulation of interleukin-17 production [inference]

negative regulation of interleukin-17 production

regulation of interleukin-23 production [inference]

negative regulation of interleukin-23 production

regulation of interleukin-6 production [inference]

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of dendritic cell cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of MHC class II biosynthetic process [inference]

positive regulation of MHC class II biosynthetic process

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of reactive oxygen species metabolic process [inference]

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of NLRP3 inflammasome complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of MHC class II biosynthetic process

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of MAPK cascade [inference]

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of platelet activation

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

regulation of macrophage activation [inference]

positive regulation of macrophage activation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

regulation of platelet activation [inference]

positive regulation of platelet activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of platelet activation

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of NLRP3 inflammasome complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of NLRP3 inflammasome complex assembly

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade [inference]

positive regulation of stress-activated MAPK cascade

positive regulation of stress-activated protein kinase signaling cascade [inference]

positive regulation of stress-activated MAPK cascade

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of smooth muscle cell migration [inference]

positive regulation of smooth muscle cell migration

positive regulation of cell migration

positive regulation of smooth muscle cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of smooth muscle cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of dendritic cell cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of type II interferon production [inference]

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-13 production [inference]

positive regulation of interleukin-13 production

regulation of interleukin-17 production [inference]

negative regulation of interleukin-17 production

regulation of interleukin-23 production [inference]

negative regulation of interleukin-23 production

regulation of interleukin-6 production [inference]

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

regulation of macrophage activation [inference]

positive regulation of macrophage activation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

regulation of platelet activation [inference]

positive regulation of platelet activation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of platelet activation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of chemokine production

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of type II interferon production

positive regulation of interleukin-1 production

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of macrophage activation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte proliferation

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of B cell proliferation

positive regulation of platelet activation

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

negative regulation of cold-induced thermogenesis

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

activation of protein kinase activity [inference]

activation of NF-kappaB-inducing kinase activity

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
ruffle	IEA
phagocytic cup	ISO
phagocytic cup	IEA
cytoplasm	ISO
cytoplasm	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

lipopolysaccharide receptor complex

membrane protein complex [inference]

lipopolysaccharide receptor complex

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

ruffle

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
lipopolysaccharide binding	ISO
lipopolysaccharide binding	IBA
lipopolysaccharide binding	IEA
lipopolysaccharide immune receptor activity	ISS
lipopolysaccharide immune receptor activity	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

protein dimerization activity [inference]

protein heterodimerization activity

lipid binding [inference]

lipopolysaccharide binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity

pattern recognition receptor activity [inference]

lipopolysaccharide immune receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Toll-like receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
immune response
immune system process
inflammatory response
toll-like receptor signaling pathway

Displaying **all 6** entries
InterPro
Cysteine-rich flanking region, C-terminal
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat
Toll/interleukin-1 receptor homology (TIR) domain superfamily
Toll/interleukin-1 receptor homology (TIR) domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9675	pulmonary emphysema	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements