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Toll-like receptor 4

Summary

UniProt ID

L0CL36

Gene Symbol

Lps
Tlr4

Gene ID

21898

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003023
Re-Glyco: L0CL36

Annotation

Keyword: Cell membrane Cell projection Disulfide bond Endosome Glycoprotein Inflammatory response Innate immunity Leucine-rich repeat NAD Receptor Repeat Signal Transmembrane helix Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	Reference
immune effector process	IEA	GO_REF
MyD88-dependent toll-like receptor signaling pathway	IEA	GO_REF
phagocytosis	IEA	GO_REF
inflammatory response	IEA	GO_REF GO_REF GO_REF
canonical NF-kappaB signal transduction

GO Hierarchy

biological process

immune system process [inference]

immune effector process

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

lymphocyte activation [inference]

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

lymphocyte activation [inference]

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

signal transduction involved in regulation of gene expression

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

ERK1 and ERK2 cascade

canonical NF-kappaB signal transduction

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

lymphocyte activation [inference]

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

response to chemical [inference]

response to lipid [inference]

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

response to peptide [inference]

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

response to nitrogen compound [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

detection of lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

detection of biotic stimulus [inference]

detection of external biotic stimulus [inference]

detection of molecule of bacterial origin [inference]

detection of lipopolysaccharide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus [inference]

cellular response to oxidised low-density lipoprotein particle stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of inflammatory response [inference]

positive regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of response to cytokine stimulus [inference]

positive regulation of response to cytokine stimulus [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of response to macrophage colony-stimulating factor [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

regulation of cellular response to macrophage colony-stimulating factor stimulus [inference]

positive regulation of cellular response to macrophage colony-stimulating factor stimulus

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway [inference]

MyD88-dependent toll-like receptor signaling pathway

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

cell surface pattern recognition receptor signaling pathway [inference]

cell surface toll-like receptor signaling pathway [inference]

toll-like receptor 4 signaling pathway

signal transduction involved in regulation of gene expression

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

MAPK cascade [inference]

ERK1 and ERK2 cascade

canonical NF-kappaB signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of matrix metallopeptidase secretion [inference]

positive regulation of matrix metallopeptidase secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion [inference]

positive regulation of matrix metallopeptidase secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of chemokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of chemokine (C-X-C motif) ligand 2 production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of interleukin-12 production [inference]

positive regulation of interleukin-12 production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of cytokine production involved in inflammatory response [inference]

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of chemokine production [inference]

positive regulation of chemokine (C-X-C motif) ligand 2 production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in inflammatory response

Displaying entries **1 - 5** of 7 in total

1

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GO Term	Evidence Code	Reference
ruffle	IEA	GO_REF
phagocytic cup	IEA	GO_REF
early endosome	IEA	GO_REF
external side of plasma membrane	IEA	GO_REF
endosome membrane	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

lipopolysaccharide receptor complex

membrane protein complex [inference]

lipopolysaccharide receptor complex

cellular anatomical structure [inference]

phagocytic cup

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

ruffle

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 6 in total

1

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GO Term	Evidence Code	Reference
lipopolysaccharide binding	IEA	GO_REF
lipopolysaccharide immune receptor activity	IEA	GO_REF
transmembrane signaling receptor activity	IEA	GO_REF GO_REF
signaling receptor binding	IEA	GO_REF
identical protein binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein dimerization activity [inference]

protein heterodimerization activity

lipid binding [inference]

lipopolysaccharide binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

pattern recognition receptor activity [inference]

lipopolysaccharide immune receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
237				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements