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MIRAGE

PAT1 homolog 1, processing body mRNA decay factor

Summary

Gene Symbol

PATL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

219988

KEGG Gene ID

PubChem

219988

Alliance of Genome Resources

HGNC:26721

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Methylation
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86TB9	PAT1-like protein 1 Protein PAT1 homolog b

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
deadenylation-dependent decapping of nuclear-transcribed mRNA	IDA
deadenylation-dependent decapping of nuclear-transcribed mRNA	IBA
deadenylation-dependent decapping of nuclear-transcribed mRNA	IEA
P-body assembly	IDA
P-body assembly	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

RNA decapping [inference]

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

RNA decapping [inference]

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

P-body assembly

cellular component assembly [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

P-body assembly

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
P-body	IDA
P-body	IBA
P-body	IEA
nucleus	IEA
cytoplasm	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

CCR4-NOT complex

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nuclear body [inference]

PML body

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

P-body

nuclear ribonucleoprotein granule [inference]

nuclear speck

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nuclear body [inference]

PML body

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

P-body

nuclear ribonucleoprotein granule [inference]

nuclear speck

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

P-body

nuclear ribonucleoprotein granule [inference]

nuclear speck

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
RNA binding	IDA
RNA binding	IBA
RNA binding	HDA
protein binding	IPI
poly(U) RNA binding	IDA

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

single-stranded RNA binding [inference]

poly-pyrimidine tract binding [inference]

poly(U) RNA binding

poly-purine tract binding [inference]

poly(G) binding

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protein PAT1 homolog 1

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
P-body assembly
deadenylation-dependent decapping of nuclear-transcribed mRNA

Displaying **all 2** entries
InterPro
Pat1-like
mRNA decay factor PAT1 domain

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Saccharomyces cerevisiae S288C	850440	SGD:S000000673

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026