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deadenylation-dependent mRNA-decapping factor PAT1

Summary

Gene Symbol

PAT1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

850440

KEGG Gene ID

PubChem

850440

Alliance of Genome Resources

SGD:S000000673

Annotation

Keyword

3D-structure
Acetylation
Cell division
Centromere
Chromosome
Cytoplasm
Kinetochore
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Repressor
Translation regulation
mRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
P25644	DNA topoisomerase 2-associated protein PAT1 Decapping activator and translational repressor PAT1 Topoisomerase II-associated protein PAT1 mRNA turnover protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
deadenylation-dependent decapping of nuclear-transcribed mRNA	IMP
deadenylation-dependent decapping of nuclear-transcribed mRNA	IBA
deadenylation-dependent decapping of nuclear-transcribed mRNA	IPI
deadenylation-dependent decapping of nuclear-transcribed mRNA	IEA
formation of translation preinitiation complex	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

RNA decapping [inference]

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

RNA decapping [inference]

mRNA methylguanosine-cap decapping [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

RNA processing [inference]

mRNA processing

cell division

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

P-body assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

formation of translation preinitiation complex

organelle assembly [inference]

membraneless organelle assembly [inference]

P-body assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

formation of translation preinitiation complex

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

formation of translation preinitiation complex

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

negative regulation of translational initiation

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

deadenylation-dependent decapping of nuclear-transcribed mRNA

negative regulation of translation [inference]

negative regulation of translational initiation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translational initiation

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
kinetochore	IDA
P-body	IDA
P-body	IMP
P-body	IBA
P-body	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

Sm-like protein family complex [inference]

Lsm1-7-Pat1 complex

ribonucleoprotein complex [inference]

ribosomal subunit [inference]

small ribosomal subunit [inference]

cytosolic small ribosomal subunit

cellular anatomical structure [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

kinetochore

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

kinetochore

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

supramolecular complex [inference]

kinetochore

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
chromatin binding	IDA
RNA binding	IDA
RNA binding	IBA
mRNA binding	IDA
mRNA binding	HDA

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

mRNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Pat1

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
P-body assembly
deadenylation-dependent decapping of nuclear-transcribed mRNA

Displaying **all 2** entries
InterPro
Pat1-like
mRNA decay factor PAT1 domain

Alliance of Genome Resources

Expression

Displaying **all 7** entries
Location	References
cytoplasm	PMID:22842922 PMID:23706738
cytoplasmic stress granule	PMID:23222640
Lsm1-7-Pat1 complex	PMID:24139796
kinetochore	PMID:23893485
nucleus	PMID:23706738
cytosolic small ribosomal subunit	PMID:10779343
P-body	PMID:12730603

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	219988	HGNC:26721

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements